Ocfentanil
Encyclopedia
Ocfentanil is an opioid
Opioid
An opioid is a psychoactive chemical that works by binding to opioid receptors, which are found principally in the central and peripheral nervous system and the gastrointestinal tract...

 analgesic
Analgesic
An analgesic is any member of the group of drugs used to relieve pain . The word analgesic derives from Greek an- and algos ....

 that is an analogue
Analog (chemistry)
In chemistry, a structural analog , also known as chemical analog or simply analog, is a compound having a structure similar to that of another one, but differing from it in respect of a certain component. It can differ in one or more atoms, functional groups, or substructures, which are replaced...

 of fentanyl and was developed in the early 1990s. It is similar to fentanyl in effects, producing strong analgesia and sedation
Sedation
Sedation is the reduction of irritability or agitation by administration of sedative drugs, generally to facilitate a medical procedure or diagnostic procedure...

, but is slightly more potent, with 3μg/kg of ocfentanil being equivalent to 5μg/kg of fentanyl.

Side effects of fentanyl analogues are similar to those of fentanyl, and include itching, nausea
Nausea
Nausea , is a sensation of unease and discomfort in the upper stomach with an involuntary urge to vomit. It often, but not always, precedes vomiting...

 and potentially serious respiratory depression which can be life-threatening.
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