Science

• Nuclear weapon
  Nuclear weapon
  A nuclear weapon is an explosive device that derives its destructive force from nuclear reactions, either fission or a combination of fission and fusion. Both reactions release vast quantities of energy from relatively small amounts of matter. The first fission bomb test released the same amount...
  
  
• Nuclear power
  Nuclear power
  Nuclear power is the use of sustained nuclear fission to generate heat and electricity. Nuclear power plants provide about 6% of the world's energy and 13–14% of the world's electricity, with the U.S., France, and Japan together accounting for about 50% of nuclear generated electricity...
  
  
• Microwaving Food
  Microwave oven
  A microwave oven is a kitchen appliance that heats food by dielectric heating, using microwave radiation to heat polarized molecules within the food...
  
  
• ICBM

Computing

• Nuke (software)
  Nuke (software)
  Nuke is a node-based compositor produced by The Foundry, and used for film and television post-production. Nuke is cross-platform, and is available for Microsoft Windows, Mac OS X, and Linux...
  
  , a node-based compositor
• Duke Nukem
  Duke Nukem
  Duke Nukem is a video game series focusing on its protagonist, Duke Nukem. Originally created by Apogee Software Ltd./3D Realms as a series of video games for the PC, the franchise expanded to games released for various consoles by third party developers...
  
  , a series of video games with a protagonist of the same name
• Nuke (gaming)
  Nuke (gaming)
  In many online video games , the term nuke can describe a spell or skill that is capable of dealing a large amount of damage to its target, which is frequently a unit. Also in the context of video games, “nuking” may also describe the act of using a nuclear weapon in the game...
  
  , a damaging attack in a role-playing game
• Nuke (warez)
  Nuke (warez)
  In the warez scene, nuke refers to labeling content as "bad", for reasons which might include unusable software, bad video/audio quality, virus-infected content, deceptively labeled content or not following the rules. Also duplicates and stolen releases from other pirates that do not attribute the...
  
  
• WinNuke
  WinNuke
  The term WinNuke refers to a remote denial-of-service attack that affected the Microsoft Windows 95, Microsoft Windows NT and Microsoft Windows 3.1x computer operating systems. It is responsible for the famous "blue screen of death"...
  
  , a Microsoft Windows exploit
• A kind of denial-of-service attack against a computer network
• Nuclear War MUD
  Nuclear War MUD
  Nuclear War MUD, abbreviated Nuke, is a MUD, a text-based online role-playing game, founded in 1992.-Game characteristics:The MUD is set in a post-apocalyptic world with cyberpunk elements. Civilization has been destroyed by a nuclear holocaust — hence the name of the MUD...
  
  , a text-based online role-playing game
• Several content management systems, including:
  • PHP-Nuke
    PHP-Nuke
    PHP-Nuke is a web-based automated news publishing and content management system based on PHP and MySQL originally authored by Franscisco Burzi. The system is controlled using a web-based user interface. PHP-Nuke was originally a fork of the Thatware news portal system.PHP-Nuke was originally...
    
    
  • PostNuke
    Zikula
    Zikula is a free open source web application framework released under the GNU General Public License. It can be used to develop robust, secure, interactive and editable websites and web based applications. Zikula is written in object oriented PHP and is fully modular...
    
    
  • DotNetNuke
    DotNetNuke
    DotNetNuke is an open source web content management system based on Microsoft .NET technology.DotNetNuke was written in VB.NET, though the developer has shifted to C# since version 6.0. It is distributed under both a Community Edition BSD-style license and commercial proprietary licenses as the...
    
    
  • RavenNuke
    Ravennuke
    RavenNuke is a content management system platform for publishing content on the World Wide Web and intranets. The system includes features such as page caching to improve performance, RSS feeds, printable versions of pages, news flashes, blogs, polls, website searching, and language...
    
    

Fiction

• Nuke (Marvel Comics), a villain with the American flag tattooed on his face
• Nuke (Squadron Supreme)
  Nuke (Squadron Supreme)
  Nuke is a superhero from Earth-712 in the fictional Marvel Universe, a member of the Squadron Supreme and later its rebooted equivalent, Supreme Power.-Fictional character biography:...
  
  , a superhero from Earth-712
• A narcotic that was made by the drug lord and cult-leader Cain, in the film Robocop 2
  RoboCop 2
  RoboCop 2 is a 1990 science fiction action film directed by Irvin Kershner and starring Peter Weller, Nancy Allen, Dan O'Herlihy, Belinda Bayer, Tom Noonan and Gabriel Damon. Set in the near future in a dystopian metropolitan Detroit, Michigan...
  
  
• Luke Snyder and Noah Mayer
  Luke Snyder and Noah Mayer
  Luke Snyder and Noah Mayer are fictional characters and a supercouple from the American CBS daytime drama As the World Turns. Luke was portrayed by Van Hansis, and Noah was portrayed by Jake Silbermann. On Internet message boards, the couple is referred to by the portmanteau "Nuke"...
  
  , a supercouple from the television series As the World Turns.