Niperotidine
Encyclopedia
Niperotidine is a histamine antagonist
selective for the H2 subtype. It was trialled as a treatment for excessive gastric acidity, but withdrawn after human trials showed liver damage
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Histamine antagonist
A histamine antagonist, commonly referred to as antihistamine, is a pharmaceutical drug that inhibits action of histamine by blocking it from attaching to histamine receptors.- Clinical effects :...
selective for the H2 subtype. It was trialled as a treatment for excessive gastric acidity, but withdrawn after human trials showed liver damage
Hepatotoxicity
Hepatotoxicity implies chemical-driven liver damage.The liver plays a central role in transforming and clearing chemicals and is susceptible to the toxicity from these agents. Certain medicinal agents, when taken in overdoses and sometimes even when introduced within therapeutic ranges, may injure...
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