New England Biolabs produces and supplies reagents for the life science industry. NEB offers 230 recombinant

Recombinant DNA

Recombinant DNA molecules are DNA sequences that result from the use of laboratory methods to bring together genetic material from multiple sources, creating sequences that would not otherwise be found in biological organisms...

 and 30 native restriction enzyme

Restriction enzyme

A Restriction Enzyme is an enzyme that cuts double-stranded DNA at specific recognition nucleotide sequences known as restriction sites. Such enzymes, found in bacteria and archaea, are thought to have evolved to provide a defense mechanism against invading viruses...

s for genomic research, as well as nicking enzymes and DNA methylases. It offers products in the areas related to proteomics

Proteomics

Proteomics is the large-scale study of proteins, particularly their structures and functions. Proteins are vital parts of living organisms, as they are the main components of the physiological metabolic pathways of cells. The term "proteomics" was first coined in 1997 to make an analogy with...

, DNA Sequencing

DNA sequencing

DNA sequencing includes several methods and technologies that are used for determining the order of the nucleotide bases—adenine, guanine, cytosine, and thymine—in a molecule of DNA....

, and drug discovery

Drug discovery

In the fields of medicine, biotechnology and pharmacology, drug discovery is the process by which drugs are discovered or designed.In the past most drugs have been discovered either by identifying the active ingredient from traditional remedies or by serendipitous discovery...

. NEB scientists conduct basic research in Molecular Biology and Parasitology and publish extensively. NEB also provides free access to research tools such as REBASE

Rebase (database)

REBASE is a database of information about restriction enzymes and DNA methyltransferases....

, InBASE, and Polbase

Polbase

Polbase is an open repository of DNA polymerase information. Polbase captures information from published research on polymerase activity, and presents it in context with related work. Polbase indexes over 5,000 references from the 1950s to the present and includes hundreds of polymerases and...

.

History

Established in 1974 as a cooperative laboratory of experienced scientists, is one of the first companies to produce restriction enzymes on a commercial scale.

Dr. Donald G. Comb is the founder and owner. In 1982 he established the NEB Foundation to support grassroots organizations working with the environment, social change, the arts, elementary education, and science.