Neuropeptide Y receptor Y2
Encyclopedia
Neuropeptide Y receptor type 2 is a protein
that in humans is encoded by the NPY2R gene
.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the NPY2R gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Agonists
- Neuropeptide YNeuropeptide YNeuropeptide Y is a 36-amino acid peptide neurotransmitter found in the brain and autonomic nervous system."NPY has been associated with a number of physiologic processes in the brain, including the regulation of energy balance, memory and learning, and epilepsy." The main effect is increased food...
(endogenous agonist, non subtype selective) - Neuropeptide Y fragment 13-36 (NPY2 selective agonist)
- 2-Thiouridine 5'-triphosphate (CAS# 35763-29-2)
- Peptide YYPeptide YYPeptide YY is a short protein released by cells in the ileum and colon in response to feeding. In humans it appears to reduce appetite.It is also known as PYY, Peptide Tyrosine Tyrosine, or Pancreatic Peptide YY3-36....
- Peptide YY 3-36 fragment
Antagonists
- BIIE-0246BIIE-0246BIIE-0246 is a drug used in scientific research which acts as a potent and selective antagonist for the Neuropeptide Y receptor Y2. It was one of the first non-peptide Y2-selective antagonists developed, and remains among the most widely used tools for studying this receptor...
(CAS# 246146-55-4) - JNJ 5207787 (CAS# 683746-68-1)
- SF 11 (CAS# 443292-81-7)