Need to Know (House)
Encyclopedia
"Need to Know" is the eleventh episode of the second season of House
House (TV series)
House is an American television medical drama that debuted on the Fox network on November 16, 2004. The show's central character is Dr. Gregory House , an unconventional and misanthropic medical genius who heads a team of diagnosticians at the fictional Princeton-Plainsboro Teaching Hospital in...

, which premiered on the Fox
Fox Broadcasting Company
Fox Broadcasting Company, commonly referred to as Fox Network or simply Fox , is an American commercial broadcasting television network owned by Fox Entertainment Group, part of Rupert Murdoch's News Corporation. Launched on October 9, 1986, Fox was the highest-rated broadcast network in the...

 network on February 7, 2006.

Plot

The episode begins by showing Margo Dalton, a "superwife". After a twinge in her arm, she begins an uncontrollable series of muscle spasms. House suspects Margo may be pregnant and gives her a paralytic so they can run some tests. The tests reveal that Margo isn't pregnant. Margo displays sudden irritability, which confirms Foreman's suspicion of Huntington's disease
Huntington's disease
Huntington's disease, chorea, or disorder , is a neurodegenerative genetic disorder that affects muscle coordination and leads to cognitive decline and dementia. It typically becomes noticeable in middle age. HD is the most common genetic cause of abnormal involuntary writhing movements called chorea...

.

Wilson confronts Stacy over her kiss with House and warns she can't toy with him. She admits she doesn't know what she's doing.

Margo has a psychotic breakdown, leading House to suspect that Margo is using cocaine
Cocaine
Cocaine is a crystalline tropane alkaloid that is obtained from the leaves of the coca plant. The name comes from "coca" in addition to the alkaloid suffix -ine, forming cocaine. It is a stimulant of the central nervous system, an appetite suppressant, and a topical anesthetic...

. Cameron and Foreman find Margo's daughter's Ritalin
Methylphenidate
Methylphenidate is a psychostimulant drug approved for treatment of attention-deficit hyperactivity disorder, postural orthostatic tachycardia syndrome and narcolepsy. It may also be prescribed for off-label use in treatment-resistant cases of lethargy, depression, neural insult and obesity...

 in the car while searching her house for drugs. House suspects they're the cause of her symptoms. When Foreman chooses not to release her until it's confirmed, House goes to visit the family. He interrogates Stella and determines she's not taking her Ritalin. Margo reveals she never gave Stella the Ritalin and instead used it herself.

House then visits Stacy, who reveals she's leaving now that Mark is getting better. House argues that she loves him more than Mark and he doesn't want her to leave. Margo is discharged, but while leaving she has a stroke and collapses. Cameron calls House with the news. It is revealed that he is in bed with Stacy at his side.

The team begins to work on diagnosing Margo's new symptoms. House suspects the fertility treatments caused endometrial cancer
Endometrial cancer
Endometrial cancer refers to several types of malignancies that arise from the endometrium, or lining, of the uterus. Endometrial cancers are the most common gynecologic cancers in the United States, with over 35,000 women diagnosed each year. The incidence is on a slow rise secondary to the...

. On the roof, Stacy meets with House. He wants to know if she is going to tell Mark about their affair, but she stalls.

Margo's initial tests for cancer come back negative, but House persists and orders a biopsy to find the suspected tumor. During Margo's biopsy, she begins to bleed from her uterus. They determine the blood is coming from her liver, leading them to suspect a tumor there instead.

While Stacy goes to Cuddy for advice on how to proceed concerning her situation with House, Mark comes to House asking for advice, concerned that he's shutting Stacy out. House goes up a flight of stairs to avoid him, but Mark tries to follow him and collapses. House refuses to help him.

House is not convinced that the symptoms indicate a liver tumor and takes another look at her history. House suspects that Margo was secretly using birth control pills to negate the fertility treatments, believing that she didn't want a child even though her husband did. The combination of Ritalin, birth control, and fertility treatments caused the tumor, which House believes should be benign. But Margo still claims she's not taking the pills and insists on undergoing surgery despite the risks. The surgery reveals the benign tumor that House suspected. Margo asks Foreman to lie to her husband and claim she can't take fertility treatments any more. Foreman refuses.

Cameron goes to House, who has her HIV test results, which are negative. House has already read it and gives it to her to read. House confronts Stacy, who reveals she's going to leave Mark for House. House tells her it's Mark who is willing to do what it takes, not him, and he can't make her happy. He worries their relationship will disintegrate once again.

Wilson sees Stacy packing up and he confronts House. Wilson points out that House sent Stacy away so he could keep feeling miserable, and so he won't have to change and lose what he thinks makes himself special. Wilson storms off as House considers what he said.

External links

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