Myosin 1G or Myo1G is a member of class I unconventional myosin

Myosin

Myosins comprise a family of ATP-dependent motor proteins and are best known for their role in muscle contraction and their involvement in a wide range of other eukaryotic motility processes. They are responsible for actin-based motility. The term was originally used to describe a group of similar...

s. Its expression is highly restricted to hematopoietic tissues and cells. It localises exclusively to the plasma membrane and is dependent on both the motor domain and the tail domain. Myo1G regulates cell elasticity possibly by interaction plasma membrane and cortical actin in Jurkat T-cells.