Multisynthetase complex auxiliary component p38
Encyclopedia
Aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 is an enzyme
that in humans is encoded by the AIMP2 gene
.
, P53
and KARS
.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the AIMP2 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
Multisynthetase complex auxiliary component p38 has been shown to interact with Parkin (ligase)Parkin (ligase)
Parkin is a protein which in humans is encoded by the PARK2 gene. The precise function of this protein is unknown; however, the protein is a component of a multiprotein E3 ubiquitin ligase complex which in turn is part of the ubiquitin-proteasome system that mediates the targeting of proteins for...
, P53
P53
p53 , is a tumor suppressor protein that in humans is encoded by the TP53 gene. p53 is crucial in multicellular organisms, where it regulates the cell cycle and, thus, functions as a tumor suppressor that is involved in preventing cancer...
and KARS
KARS (gene)
Lysyl-tRNA synthetase is an enzyme that in humans is encoded by the KARS gene.-Interactions:KARS has been shown to interact with Multisynthetase complex auxiliary component p38. Physiological trigger such as immunological activation results in the phosphorylation of LysRS is on serine residues...
.