Mosuke Murata
Encyclopedia
is a Japanese
Japanese people
The are an ethnic group originating in the Japanese archipelago and are the predominant ethnic group of Japan. Worldwide, approximately 130 million people are of Japanese descent; of these, approximately 127 million are residents of Japan. People of Japanese ancestry who live in other countries...

 dermatologist and was the designator of erythema nodosum leprosum (ENL)(1912), the type 2 lepra
Leprosy
Leprosy or Hansen's disease is a chronic disease caused by the bacteria Mycobacterium leprae and Mycobacterium lepromatosis. Named after physician Gerhard Armauer Hansen, leprosy is primarily a granulomatous disease of the peripheral nerves and mucosa of the upper respiratory tract; skin lesions...

 reaction.

Life and works

Mosuke Murata joined the Zensho Byoin, now Tama Zenshoen Sanatorium
Tama Zenshoen Sanatorium
Tama Zenshoen Sanatorium, or National Sanatorium Tama Zenshoen, is a sanatorium for leprosy or ex-leprosy patients situated in Higashimurayama-shi, Tokyo-to, Japan starting in 1909.-Background:...

 in 1909. The chief dermatologist was Kensuke Mitsuda
Kensuke Mitsuda
was a Japanese leprologist and director of the Tama Zenshoen Sanatorium and the National Sanatorum Nagashima Aiseien. He had been at the frontier of leprosy policy of Japan. He was given the Order of Cultural Merits and Damien-Dutton Award...

 and there was another doctor Chin. Murata belonged to the surgery section, and studied leprosy
Leprosy
Leprosy or Hansen's disease is a chronic disease caused by the bacteria Mycobacterium leprae and Mycobacterium lepromatosis. Named after physician Gerhard Armauer Hansen, leprosy is primarily a granulomatous disease of the peripheral nerves and mucosa of the upper respiratory tract; skin lesions...

. He was known for naming a hot nodule of leprosy, erythema nodosum leprosum (ENL). There was need to differentiate it from other types of erythema nodosum, which is usually seen in the lower parts of the body. In his paper, he thanked Kensuke Mitsuda
Kensuke Mitsuda
was a Japanese leprologist and director of the Tama Zenshoen Sanatorium and the National Sanatorum Nagashima Aiseien. He had been at the frontier of leprosy policy of Japan. He was given the Order of Cultural Merits and Damien-Dutton Award...

 for allowing him to study a total of 67 cases. After writing papers, he went into private practice in 1914.

Erythema Nodosum Leprosum

Erythema nodosum leprosum is one of the most frequently used terms in the science of leprosy. It is an immune-mediated complication of leprosy presenting with inflammatory skin nodules. Immune complex production and deposition as well as complement activation have long been regarded as the principal etiology of ENL. ENL is characterised by an inflammatory infiltrate of neutrophils with vasculitis. There is deposition of immune complexes and complement together with Mycobacterium leprae antigens in the skin.

Term's origin

William Jopling
William Jopling
William Jopling was a leprologist who together with Ridley D.S. proposed the Ridley-Jopling classification of leprosy , and wrote the widely read textbook of "Handbook of Leprosy" which had a fifth edition...

 wanted to know who named this condition erythema nodosum leprosum, and asked every visitor to his Jordan Hospital, a leprosy hospital (1950–1967) near London. Yoshinobu Hayashi, the director of Tama Zenshoen Sanatorium
Tama Zenshoen Sanatorium
Tama Zenshoen Sanatorium, or National Sanatorium Tama Zenshoen, is a sanatorium for leprosy or ex-leprosy patients situated in Higashimurayama-shi, Tokyo-to, Japan starting in 1909.-Background:...

visited the hospital and brought the information

Other works

  • Mitsuda K, Murata M: On the serum reactions in leprosy. Jpn J Dermatol Urol 11,7(number).1911.
  • Murata M: Leprosy patients in Kusatsu Town. Jpn J Dermatol Urol 11,17,1911.
  • Murata M:Specific reactive substances in leprosy exudate. Jpn J Dermatol Urol 12,9,1912.
  • Murata M:Leprosy bacilli in vesicles and histological studies on smallpox vaccine vesicles. Jpn J Dermatol Urol 13,6,1913.
  • Murata M:Diagnostic criteria of leprosy in childhood. Kinsei Igaku, Volume 2, Number 1.
The source of this article is wikipedia, the free encyclopedia.  The text of this article is licensed under the GFDL.
 
x
OK