Monocytic leukemia
Encyclopedia
Monocytic leukemia is a type of myeloid leukemia
characterized by a dominance of monocyte
s in the marrow
. When the monocytic cells are predominantly monoblast
s, it is subclassified into monoblastic leukemia.
Like myeloid leukemia
, monocytic leukemia is almost always broken down into "acute" and "chronic":
Acute monocytic leukemia is far more commonly referenced than the chronic variety. However, the chronic variety is a valid diagnostic entry.
Myeloid leukemia
Myeloid leukemia is a type of leukemia affecting myeloid tissue.Types include:* Acute myeloid leukemia* Chronic myelogenous leukemia...
characterized by a dominance of monocyte
Monocyte
Monocytes are a type of white blood cell and are part of the innate immune system of vertebrates including all mammals , birds, reptiles, and fish. Monocytes play multiple roles in immune function...
s in the marrow
Bone marrow
Bone marrow is the flexible tissue found in the interior of bones. In humans, bone marrow in large bones produces new blood cells. On average, bone marrow constitutes 4% of the total body mass of humans; in adults weighing 65 kg , bone marrow accounts for approximately 2.6 kg...
. When the monocytic cells are predominantly monoblast
Monoblast
Monoblasts are normally found in bone marrow and do not appear in the normal peripheral blood. They mature into monocytes which, in turn, develop into macrophages.-Structure:...
s, it is subclassified into monoblastic leukemia.
Like myeloid leukemia
Myeloid leukemia
Myeloid leukemia is a type of leukemia affecting myeloid tissue.Types include:* Acute myeloid leukemia* Chronic myelogenous leukemia...
, monocytic leukemia is almost always broken down into "acute" and "chronic":
- acute monocytic leukemiaAcute monocytic leukemiaAcute monocytic leukemia is considered a type of acute myeloid leukemia.-Diagnosis:In order to fulfill World Health Organization criteria for AML-5, a patient must have greater than 20% blasts in the bone marrow, and of these, greater than 80% must be of the monocytic lineage...
- chronic monocytic leukemia
Acute monocytic leukemia is far more commonly referenced than the chronic variety. However, the chronic variety is a valid diagnostic entry.