Mitotic index
Encyclopedia
Mitotic index is a measure for the proliferation status of a cell population. It is defined as the ratio between the number of cell
Cell (biology)
The cell is the basic structural and functional unit of all known living organisms. It is the smallest unit of life that is classified as a living thing, and is often called the building block of life. The Alberts text discusses how the "cellular building blocks" move to shape developing embryos....

s in mitosis
Mitosis
Mitosis is the process by which a eukaryotic cell separates the chromosomes in its cell nucleus into two identical sets, in two separate nuclei. It is generally followed immediately by cytokinesis, which divides the nuclei, cytoplasm, organelles and cell membrane into two cells containing roughly...

and the total number of cells.
The mitotic index is an important prognostic factor predicting both overall survival and response to chemotherapy in most types of cancer. It may lose much of its predictive value for elderly populations, for example a low mitotic index loses any prognostic value for women over 70 years with breast cancer.
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