Mildronate
Encyclopedia
Not to be confused with Medronate, a bisphosphonate that forms a complex with radioactive technetium to be used as a radiopharmaceutical.

Mildronate is an antischemic agent of a metabolic action (cardioprotector) produced by Grindex in Latvia
Latvia
Latvia , officially the Republic of Latvia , is a country in the Baltic region of Northern Europe. It is bordered to the north by Estonia , to the south by Lithuania , to the east by the Russian Federation , to the southeast by Belarus and shares maritime borders to the west with Sweden...

. The active substance is trimethylhydrazinium propionate dihydrate.

Indications

  • Cardiovascular diseases: chronic coronary heart disease, stable angina pectoris,chronic heart failure, functional cardiovascular disturbances,cardiomyopathy.
  • Acute and chronic ischemic cerebrovascular disturbances.
  • Mildronate is used also in the cases of decreased performance, physical and psychoemotional overload, and during recovery process.

Further reading

  • Mildronate improves peripheral circulation in patients with chronic heart failure: results of a clinical trial (the first report); Vilnis Dzerve,*, Dace Matisone, Indulis Kukulis, Janina Romanova,Lilita Putane, Virginija Grabauskiene˙, Ilze Skarda, Dace Berzina, Jurgis Strautmanis ; http://www.seminarsincardiology.com/pdf/Seminars-2005-11-2-56-64.pdf
  • Mildronate improves the exercise tolerance in patients with stable angina: results of a long term clinical trial ; http://www.grindeks.lv/mce/uploads/mici.pdf
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