Milacemide
Encyclopedia
Milacemide is a MAO-B inhibitor and glycine
prodrug
. It has been studied for its effects on human memory and as a potential treatment for the symptoms of Alzheimer's disease
. Early clinical trials, however, showed no positive results.
Glycine
Glycine is an organic compound with the formula NH2CH2COOH. Having a hydrogen substituent as its 'side chain', glycine is the smallest of the 20 amino acids commonly found in proteins. Its codons are GGU, GGC, GGA, GGG cf. the genetic code.Glycine is a colourless, sweet-tasting crystalline solid...
prodrug
Prodrug
A prodrug is a pharmacological substance administered in an inactive form. Once administered, the prodrug is metabolised in vivo into an active metabolite, a process termed bioactivation. The rationale behind the use of a prodrug is generally for absorption, distribution, metabolism, and...
. It has been studied for its effects on human memory and as a potential treatment for the symptoms of Alzheimer's disease
Alzheimer's disease
Alzheimer's disease also known in medical literature as Alzheimer disease is the most common form of dementia. There is no cure for the disease, which worsens as it progresses, and eventually leads to death...
. Early clinical trials, however, showed no positive results.