Mikael Bols
Encyclopedia
Mikael Bols is a synthetic organic chemist
Organic chemistry
Organic chemistry is a subdiscipline within chemistry involving the scientific study of the structure, properties, composition, reactions, and preparation of carbon-based compounds, hydrocarbons, and their derivatives...

 who is mainly known for his work on carbohydrates and artificial enzymes.

Early life

Mikael Bols was born and grew up in Copenhagen, Denmark. He attended high school (Gentofte Statskole) from 1977-1980, and took a degree as chemical engineer at the Technical University of Denmark
Technical University of Denmark
The Technical University of Denmark , often simply referred to as DTU, is a university just north of Copenhagen, Denmark. It was founded in 1829 at the initiative of Hans Christian Ørsted as Denmark's first polytechnic, and is today ranked among Europe's leading engineering institutions, and the...

 from 1980-1985.

Professional career

From 1985 to 1988 Bols did PhD with Professor Inge Lundt at the Technical University of Denmark
Technical University of Denmark
The Technical University of Denmark , often simply referred to as DTU, is a university just north of Copenhagen, Denmark. It was founded in 1829 at the initiative of Hans Christian Ørsted as Denmark's first polytechnic, and is today ranked among Europe's leading engineering institutions, and the...

. From 1988-1989 he did a post doc with professor Walter Szarek at Queens University before joining Leo Pharmaceuticals in 1989. From 1991-1995 he was Ass. Prof. at DTU only interrupted by a visit in the last 6 month of 1994 Gilbert Stork
Gilbert Stork
Gilbert Stork is a U.S. organic chemist. He is the Eugene Higgins Professor of Chemistry Emeritus at Columbia University. The Stork enamine synthesis is named in his honor.-Education:...

's group at Columbia University
Columbia University
Columbia University in the City of New York is a private, Ivy League university in Manhattan, New York City. Columbia is the oldest institution of higher learning in the state of New York, the fifth oldest in the United States, and one of the country's nine Colonial Colleges founded before the...

 From 1995-2000 he was Assoc. Prof. (Lektor) at University of Aarhus
University of Aarhus
Aarhus University , located in the city of Aarhus, Denmark, is Denmark's second oldest and second largest university...

 during which period he became Dr. Scient. (1997). From 1998-2000 and from 2004-2006 he was Head of the chemistry department at university of Aarhus. From 2000-2005 he became Lundbeckfondsprofessor and subsequently (2005-2007) ordiniary professor. In 2007 he ´became professor and Head of department of the Department of Chemistry at University of Copenhagen
University of Copenhagen
The University of Copenhagen is the oldest and largest university and research institution in Denmark. Founded in 1479, it has more than 37,000 students, the majority of whom are female , and more than 7,000 employees. The university has several campuses located in and around Copenhagen, with the...

.

Achievements

The discovery of isofagomine and related glycosidase inhibitors, the discovery of stereoelectronic substituent effects and superarmed glycosyl donor
Glycosyl donor
A glycosyl donor is a carbohydrate mono- or oligosaccharide that will react with a suitable glycosyl acceptor to form a new glycosidic bond. By convention, the donor is the member of this pair that contains the resulting anomeric carbon of the new glycosidic bond...

s, the creation of artificial enzymes that cause large rate increases., and writing the book carbohydrate builiding blocks about using carbohydrates as a chirality source in synthesis.
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