Michelle Khine
Encyclopedia
Michelle Khine, Ph.D.
Ph.D.
A Ph.D. is a Doctor of Philosophy, an academic degree.Ph.D. may also refer to:* Ph.D. , a 1980s British group*Piled Higher and Deeper, a web comic strip*PhD: Phantasy Degree, a Korean comic series* PhD Docbook renderer, an XML renderer...

 is a distinguished scientist and innovator at the University of California, Irvine
University of California, Irvine
The University of California, Irvine , founded in 1965, is one of the ten campuses of the University of California, located in Irvine, California, USA...

, founder and Chief Technology Officer of Fluxion Biosciences Inc., the scientific founder of the Shrink nano-technology platform, as well as the Assistant and Founding Professor of the School of Engineering at UC Merced
University of California, Merced
The University of California, Merced, commonly referred to as UC Merced or UCM, is the tenth and newest of the University of California campuses. Located in the San Joaquin Valley in unincorporated Merced County, California, near Merced, UC Merced was the first American research university to...

. Khine, an assistant biomedical engineering professor in the Henry Samueli School of Engineering
Henry Samueli School of Engineering
The Henry Samueli School of Engineering is the academic unit of the University of California, Irvine that oversees academic research and teaching in various disciplines of the field of engineering...

, is responsible for experimenting with childhood toys Shrinky Dinks
Shrinky Dinks
Shrinky Dinks are a children's toy/activity kit consisting of large flexible sheets which, when heated in an oven, shrink to small hard plates without altering their color or shape. They reached the height of their popularity in the 1980s...

 to build microfluidic channels. Her research has enabled technological advances in industries including biological research and medical diagnostics.

Khine is a widely published researcher, with multiple patents grants and honors including the 2009 MIT Technology Review
Technology Review
Technology Review is a magazine published by the Massachusetts Institute of Technology. It was founded in 1899 as "The Technology Review", and was re-launched without the "The" in its name on April 23, 1998 under then publisher R. Bruce Journey...

: TR35
TR35
The TR35 is an annual list published by MIT Technology Review magazine, naming the world's top 35 innovators under the age of 35.Some of the most famous winners of the award include Larry Page and Sergey Brin , Linus Torvalds , Jerry Yang , Jonathan Ive , Mark Zuckerberg...

 Award: Selected as Top 35 Innovator under 35 in the world. Michelle Khine is also on several review committees, most notable being the Center for Scientific Review
Center for Scientific Review
The Center for Scientific Review or CSR is the portal for United States National Institutes of Health grant applications and their review for scientific merit. The CSR organizes the peer review groups or study sections that evaluate the majority of the research grant applications sent to NIH...

 at the National Institutes of Health
National Institutes of Health
The National Institutes of Health are an agency of the United States Department of Health and Human Services and are the primary agency of the United States government responsible for biomedical and health-related research. Its science and engineering counterpart is the National Science Foundation...

.

Education

Michelle received her Bachelor of Science
Bachelor of Science
A Bachelor of Science is an undergraduate academic degree awarded for completed courses that generally last three to five years .-Australia:In Australia, the BSc is a 3 year degree, offered from 1st year on...

 in 1999 and Master of Science
Master of Science
A Master of Science is a postgraduate academic master's degree awarded by universities in many countries. The degree is typically studied for in the sciences including the social sciences.-Brazil, Argentina and Uruguay:...

 in 2001, under Dennis Lieu, in Mechanical Engineering from University of California, Berkeley
University of California, Berkeley
The University of California, Berkeley , is a teaching and research university established in 1868 and located in Berkeley, California, USA...

. Michelle continued her education at UC Berkeley and UCSF
University of California, San Francisco
The University of California, San Francisco is one of the world's leading centers of health sciences research, patient care, and education. UCSF's medical, pharmacy, dentistry, nursing, and graduate schools are among the top health science professional schools in the world...

 receiving her PhD in 2005, under Luke P Lee, in Bioengineering. While in graduate school, she worked at Sandia National Laboratories
Sandia National Laboratories
The Sandia National Laboratories, managed and operated by the Sandia Corporation , are two major United States Department of Energy research and development national laboratories....

 as a MESA Fellow as well as co-founded Fluxion Biosciences (San Francisco, Ca), which was based on her dissertation work.

Selected honors and awards

In November 2000 Michelle Khine and fellow collegiate Melodie Metzger set a world speed record using the UC Berkeley Human Powered Vehicle (Bearacuda), they reached a top speed of 35.6 miles per hour (57.29 km/h) to take the tandem record in the Women's 200 meter flying start speed trial

In September 2009, Michelle was honored with the 2009 MIT Technology Review TR35
TR35
The TR35 is an annual list published by MIT Technology Review magazine, naming the world's top 35 innovators under the age of 35.Some of the most famous winners of the award include Larry Page and Sergey Brin , Linus Torvalds , Jerry Yang , Jonathan Ive , Mark Zuckerberg...

Award: Selected as Top 35 Innovator under 35 in the world.

Selected peer-reviewed publications

  • Ionescu-Zanetti C., Blatz A., Khine, M., “Electrophoresis-Assisted Single-Cell Electroporation for Efficient Intracellular Delivery”, Biomed Microdevices. 10(1):113-6, 2008.

  • Grimes A., Breslauer D.N, Long M., Pegan J., Lee L.P., Khine, M., “Shrinky-Dink Microfluidics: Rapid Generation of Deep and Rounded Patterns”, Lab on a Chip. 8(1):170-2, 2008. Highlighted in Chemical and Engineering News, Chemical Technology, on the Front page of American Chemical Society Homepage, (acs.org), front page of Lab on a Chip Homepage, and Wired. Most accessed paper January 2008. Lab on a Chip

  • Chen, C.S., Breslauer, D.N., Luna, J.I., Grimes, A., Chin, W.C., Lee, L.P, Khine M., “Shrinky Dink Microfluidics: 3-D Polystyrene Chips,” Lab on a Chip, 8, 622–624, 2008. Highlighted in Nature Medicine (May 2008). Lab on a Chip

  • Nguyen, D., Pegan, J., Sa, S., McCloskey,K.E., Manilay, J.O., Khine, M.,”Shrink-Induced Honeycomb Microwells for Uniform Embryoid Bodies” accepted to Lab on a Chip. Lab on a Chip

External links



UC Irvine Faculty: Michelle Khine

MIT 2009 TR35: Michelle Khine

Toaster oven helps researchers toy with microfluidics

Shrink Nanotechnologies Team
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