Michael Waterman
Encyclopedia
Professor Michael S. Waterman is a scientist at the University of Southern California
(USC), where he holds an Endowed Associates Chair in Biological Sciences, Mathematics and Computer Science. He previously held positions at Los Alamos National Laboratory
and Idaho State University
. He grew up near Bandon, Oregon
and earned a bachelor's degree in Mathematics from Oregon State University
, followed by a doctorate in statistics
and probability
from Michigan State University
in 1969.
Waterman is one of the founders and current leaders in the area of computational biology
. He focuses on applying mathematics, statistics, and computer science techniques to various problems in molecular biology
. His work has contributed to some of the most widely-used tools in the field. In particular, the Smith-Waterman algorithm (developed with Temple Smith) is the basis for many sequence comparison programs. In 1988, Waterman and Eric Lander
published a landmark paper describing a mathematical model for fingerprint mapping. This work formed one of the theoretical cornerstones for many of the later DNA mapping and sequencing projects, especially the Human Genome Project
.
With Sorin Istrail and Pavel A. Pevzner
, he began the international conference Research in Computational Biology (RECOMB), and he is a founding editor of Journal of Computational Biology
. He is an elected Fellow of the American Academy of Art and Sciences since 1995, and was elected to the United States National Academy of Sciences in 2001. Since 2005, he is an elected Academician of the French Académie des Sciences. Waterman also authored one of the earliest textbooks in the field: Introduction to Computational Biology.
University of Southern California
The University of Southern California is a private, not-for-profit, nonsectarian, research university located in Los Angeles, California, United States. USC was founded in 1880, making it California's oldest private research university...
(USC), where he holds an Endowed Associates Chair in Biological Sciences, Mathematics and Computer Science. He previously held positions at Los Alamos National Laboratory
Los Alamos National Laboratory
Los Alamos National Laboratory is a United States Department of Energy national laboratory, managed and operated by Los Alamos National Security , located in Los Alamos, New Mexico...
and Idaho State University
Idaho State University
Idaho State University is a public university located in Pocatello, Idaho. It has outreach programs in Coeur d'Alene, Idaho Falls, Boise, and Twin Falls....
. He grew up near Bandon, Oregon
Bandon, Oregon
- Economy :Like many communities on the Oregon coast, Bandon had significant fishing and timber industries, which were greatly diminished by the 1980s, though some remnants still exist. Bandon's current economy revolves around wood products, fishing, tourism, and agriculture...
and earned a bachelor's degree in Mathematics from Oregon State University
Oregon State University
Oregon State University is a coeducational, public research university located in Corvallis, Oregon, United States. The university offers undergraduate, graduate and doctoral degrees and a multitude of research opportunities. There are more than 200 academic degree programs offered through the...
, followed by a doctorate in statistics
Statistics
Statistics is the study of the collection, organization, analysis, and interpretation of data. It deals with all aspects of this, including the planning of data collection in terms of the design of surveys and experiments....
and probability
Probability
Probability is ordinarily used to describe an attitude of mind towards some proposition of whose truth we arenot certain. The proposition of interest is usually of the form "Will a specific event occur?" The attitude of mind is of the form "How certain are we that the event will occur?" The...
from Michigan State University
Michigan State University
Michigan State University is a public research university in East Lansing, Michigan, USA. Founded in 1855, it was the pioneer land-grant institution and served as a model for future land-grant colleges in the United States under the 1862 Morrill Act.MSU pioneered the studies of packaging,...
in 1969.
Waterman is one of the founders and current leaders in the area of computational biology
Computational biology
Computational biology involves the development and application of data-analytical and theoretical methods, mathematical modeling and computational simulation techniques to the study of biological, behavioral, and social systems...
. He focuses on applying mathematics, statistics, and computer science techniques to various problems in molecular biology
Molecular biology
Molecular biology is the branch of biology that deals with the molecular basis of biological activity. This field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry...
. His work has contributed to some of the most widely-used tools in the field. In particular, the Smith-Waterman algorithm (developed with Temple Smith) is the basis for many sequence comparison programs. In 1988, Waterman and Eric Lander
Eric Lander
Eric Steven Lander is a Professor of Biology at the Massachusetts Institute of Technology , a member of the Whitehead Institute, and director of the Broad Institute of MIT and Harvard who has devoted his career toward realizing the promise of the human genome for medicine. He is co-chair of U.S...
published a landmark paper describing a mathematical model for fingerprint mapping. This work formed one of the theoretical cornerstones for many of the later DNA mapping and sequencing projects, especially the Human Genome Project
Human Genome Project
The Human Genome Project is an international scientific research project with a primary goal of determining the sequence of chemical base pairs which make up DNA, and of identifying and mapping the approximately 20,000–25,000 genes of the human genome from both a physical and functional...
.
With Sorin Istrail and Pavel A. Pevzner
Pavel A. Pevzner
Pavel A. Pevzner is the Ronald R. Taylor Professor of Computer Science and Director of the NIH Center for Computational Mass Spectrometry at University of California San Diego...
, he began the international conference Research in Computational Biology (RECOMB), and he is a founding editor of Journal of Computational Biology
Journal of Computational Biology
The Journal of Computational Biology is a peer-reviewed scientific journal dedicated to computational biology and bioinformatics. The journal is published in 10 printed issues per year by Mary Ann Liebert....
. He is an elected Fellow of the American Academy of Art and Sciences since 1995, and was elected to the United States National Academy of Sciences in 2001. Since 2005, he is an elected Academician of the French Académie des Sciences. Waterman also authored one of the earliest textbooks in the field: Introduction to Computational Biology.