Methylenedioxybenzylpiperazine
Encyclopedia
1-piperazine (MDBZP; Piperonylpiperazine) is a psychoactive drug
Psychoactive drug
A psychoactive drug, psychopharmaceutical, or psychotropic is a chemical substance that crosses the blood–brain barrier and acts primarily upon the central nervous system where it affects brain function, resulting in changes in perception, mood, consciousness, cognition, and behavior...

 of the piperazine
Piperazine
Piperazine is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms. Piperazine exists as small alkaline deliquescent crystals with a saline taste....

 chemical class related to benzylpiperazine
Benzylpiperazine
Benzylpiperazine is a recreational drug with euphoric, stimulant properties. The effects produced by BZP are comparable to those produced by amphetamine. Adverse effects have been reported following its use including acute psychosis, renal toxicity, and seizures...

 (BZP). In the book PiHKAL
PiHKAL
PiHKAL: A Chemical Love Story is a book by Dr. Alexander Shulgin and Ann Shulgin which was published in 1991. The subject of the work is psychoactive phenethylamine chemical derivatives, notably those that act as psychedelics and/or empathogen-entactogens...

 it is speculated that MDBZP might have effects similar to the drug 3,4-methylenedioxy-N-methylamphetamine (MDMA; "Ecstasy") because of the presence of the 3,4-methylenedioxy group on the benzene ring; however, once the compound was tested in humans this theory was shown to be incorrect.

MDBZP has been sold as a "designer drug
Designer drug
Designer drug is a term used to describe drugs that are created to get around existing drug laws, usually by preparing analogs or derivatives of existing drugs by modifying their chemical structure to varying degrees, or less commonly by finding drugs with entirely different chemical structures...

" with supposed recreational properties, and has even been found as an ingredient in street "Ecstasy" pills. However, MDBZP is only a very mild stimulant, and does not produce euphoria
Euphoria
Euphoria is an emotional and mental state defined as a sense of great elation and well being.Euphoria may also refer to:* Euphoria , a genus of scarab beetles* Euphoria, a genus name previously used for the longan and other trees...

, empathogenic or psychedelic
Psychedelic
The term psychedelic is derived from the Greek words ψυχή and δηλοῦν , translating to "soul-manifesting". A psychedelic experience is characterized by the striking perception of aspects of one's mind previously unknown, or by the creative exuberance of the mind liberated from its ostensibly...

 effects. The prominent side effects produced by MDBZP are dizziness
Dizziness
Dizziness refers to an impairment in spatial perception and stability. The term is somewhat imprecise. It can be used to mean vertigo, presyncope, disequilibrium, or a non-specific feeling such as giddiness or foolishness....

, nausea
Nausea
Nausea , is a sensation of unease and discomfort in the upper stomach with an involuntary urge to vomit. It often, but not always, precedes vomiting...

 and headaches, but at high doses it has been known to cause convulsions. MDBZP thus has all of the negative side effects of other piperazine derivatives, but without any of the positive effects that might make these drugs desirable to consumers.

See also

  • 1-Benzylpiperazine (BZP)
  • 1-Methyl-4-benzylpiperazine
    1-Methyl-4-benzylpiperazine
    MBZP is a stimulant drug which is a derivative of benzylpiperazine. MBZP has been sold as an ingredient in legal recreational drugs known as "Party pills", initially in New Zealand and subsequently in other countries around the world.The effects of MBZP are very similar to those of BZP, but the...

     (MBZP)
  • 1,4-Dibenzylpiperazine (DBZP)
  • 3-Chlorophenylpiperazine
    1-(3-Chlorophenyl)piperazine
    meta-Chlorophenylpiperazine is a psychoactive drug of the phenylpiperazine class. It was initially developed in the late-1970s and used in scientific research before being sold as a designer drug in the mid-2000s...

     (mCPP)
  • 3-Trifluoromethylphenylpiperazine (TFMPP)
  • 4-Bromo-2,5-dimethoxy-1-benzylpiperazine (2C-B-BZP)
  • 4-Fluorophenylpiperazine
    PFPP
    para-Fluorophenylpiperazine is a piperazine derivative with mildly psychedelic and euphoriant effects...

     (pFPP)
  • 4-Methoxyphenylpiperazine
    MeOPP
    para-Methoxyphenylpiperazine is a piperazine derivative with stimulant effects which has been sold as an ingredient in "Party pills", initially in New Zealand and subsequently in other countries around the world.MeOPP has been found in vitro to inhibit the reuptake and induce the release of the...

     (MeOPP)
  • Piribedil
    Piribedil
    Piribedil is an antiparkinsonian agent and piperazine derivative which acts as a D2 and D3 receptor agonist...

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