Methylation induced premeiotically
Encyclopedia
In molecular biology
, methylation induced premeiotically (MIP) is a process by which cytosines
within repeated DNA
sequences are de novo methylated prior to the sexual cycle. This process was first described in the ascomycete Ascobolus immersens. MIP is dependent upon the gene masc1 which encodes a cytosine methyltransferase-like protein.
At least one major function of the process appears to be genome defense. Related functions have been found in other fungi, including Neurospora and Aspergillis species.
Molecular biology
Molecular biology is the branch of biology that deals with the molecular basis of biological activity. This field overlaps with other areas of biology and chemistry, particularly genetics and biochemistry...
, methylation induced premeiotically (MIP) is a process by which cytosines
Cytosine
Cytosine is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine . It is a pyrimidine derivative, with a heterocyclic aromatic ring and two substituents attached . The nucleoside of cytosine is cytidine...
within repeated DNA
DNA
Deoxyribonucleic acid is a nucleic acid that contains the genetic instructions used in the development and functioning of all known living organisms . The DNA segments that carry this genetic information are called genes, but other DNA sequences have structural purposes, or are involved in...
sequences are de novo methylated prior to the sexual cycle. This process was first described in the ascomycete Ascobolus immersens. MIP is dependent upon the gene masc1 which encodes a cytosine methyltransferase-like protein.
At least one major function of the process appears to be genome defense. Related functions have been found in other fungi, including Neurospora and Aspergillis species.