Methotrexate-induced papular eruption
Encyclopedia
Methotrexate-induced papular eruption appears in patients being treated with methotrexate
, such as those with rheumatic disease, presenting with erythematous indurated papules, usually located on the proximal extremities
.
It has been suggested that it may represent a Cutaneous small-vessel vasculitis
.
Methotrexate
Methotrexate , abbreviated MTX and formerly known as amethopterin, is an antimetabolite and antifolate drug. It is used in treatment of cancer, autoimmune diseases, ectopic pregnancy, and for the induction of medical abortions. It acts by inhibiting the metabolism of folic acid. Methotrexate...
, such as those with rheumatic disease, presenting with erythematous indurated papules, usually located on the proximal extremities
Proximal phalanges
Proximal phalanges are bones found in the limbs of most vertebrates. In humans, they are the bones at the base of a toe or finger, the prominent, knobby ends of which are often called the knuckles....
.
It has been suggested that it may represent a Cutaneous small-vessel vasculitis
Cutaneous small-vessel vasculitis
Cutaneous small-vessel vasculitis is inflammation of small blood vessels , characterized by palpable purpura. It is the most common vasculitis seen in clinical practice...
.