Methisazone
Encyclopedia
Methisazone is an antiviral drug
Antiviral drug
Antiviral drugs are a class of medication used specifically for treating viral infections. Like antibiotics for bacteria, specific antivirals are used for specific viruses...

 that works by inhibiting mRNA and protein synthesis, especially in pox viruses. It has been used in the past to treat smallpox
Smallpox
Smallpox was an infectious disease unique to humans, caused by either of two virus variants, Variola major and Variola minor. The disease is also known by the Latin names Variola or Variola vera, which is a derivative of the Latin varius, meaning "spotted", or varus, meaning "pimple"...

.

Methisazone has been described as being used in prophylaxis since at least 1965.
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