Menatetrenone
Encyclopedia
Menatetrenone also known as MK4, is a menaquinone
compound used as a hemostatic agent and as adjunctive therapy for the pain of osteoporosis
. It is marketed for the latter indication in Japan
by Eisai Co.
, under the trade name Glakay.
Menatetrenone (MK4) is one of the nine forms of vitamin K2.
Vitamin K
Vitamin K is a group of structurally similar, fat soluble vitamins that are needed for the posttranslational modification of certain proteins required for blood coagulation and in metabolic pathways in bone and other tissue. They are 2-methyl-1,4-naphthoquinone derivatives...
compound used as a hemostatic agent and as adjunctive therapy for the pain of osteoporosis
Osteoporosis
Osteoporosis is a disease of bones that leads to an increased risk of fracture. In osteoporosis the bone mineral density is reduced, bone microarchitecture is deteriorating, and the amount and variety of proteins in bone is altered...
. It is marketed for the latter indication in Japan
Japan
Japan is an island nation in East Asia. Located in the Pacific Ocean, it lies to the east of the Sea of Japan, China, North Korea, South Korea and Russia, stretching from the Sea of Okhotsk in the north to the East China Sea and Taiwan in the south...
by Eisai Co.
Eisai Co.
is a Japanese pharmaceutical company, ranking among the top 25 in the world by revenue and achieving $8 billion USD in sales for the fiscal 2008 year. Headquartered in Tokyo, Japan, it has some 10,000 employees, among them about 1,500 in research. Eisai is a member of the Topix 100 and Nikkei 225...
, under the trade name Glakay.
Menatetrenone (MK4) is one of the nine forms of vitamin K2.