Route 78 is a short south–north highway in northeastern Franklin County

Franklin County, Massachusetts

-Demographics:As of the census of 2000, there were 71,535 people, 29,466 households, and 18,416 families residing in the county. The population density was 102 people per square mile . There were 31,939 housing units at an average density of 46 per square mile...

. Massachusetts

Massachusetts

The Commonwealth of Massachusetts is a state in the New England region of the northeastern United States of America. It is bordered by Rhode Island and Connecticut to the south, New York to the west, and Vermont and New Hampshire to the north; at its east lies the Atlantic Ocean. As of the 2010...

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Route 78 begins at Route 2A in Orange

Orange, Massachusetts

Orange is a town in Franklin County, Massachusetts, United States. The population was 7,839 at the 2010 census. It is part of the Springfield, Massachusetts Metropolitan Statistical Area.Part of the town is included in the census-designated place of Orange....

, just north of the Springfield Terminal railroad tracks and the Millers River

Millers River

The Millers River is a river in northern Massachusetts, originating in Ashburnham and joining the Connecticut River just downstream from Millers Falls, Massachusetts...

. After 1.4 miles (2.3 km), the route enters the town of Warwick

Warwick, Massachusetts

Warwick is a town in Franklin County, Massachusetts, United States. The population was 750 at the 2000 census. It is part of the Springfield, Massachusetts Metropolitan Statistical Area.- History :...

. The route passes by several portions of Warwick State Forest and through the town center, before passing Mount Grace

Mount Grace

Mount Grace, , is a prominent monadnock located in north central Massachusetts in the town of Warwick, approximately two miles south of the New Hampshire border. The mountain is rugged and largely wooded, but a firetower on the summit provides expansive views of the surrounding rural countryside....

 and entering Winchester, New Hampshire

Winchester, New Hampshire

Winchester is a town in Cheshire County, New Hampshire, United States. The population was 4,341 at the 2010 census. The primary settlement in the town, where 1,733 people resided at the 2010 census, is defined by the U.S. Census Bureau as the Winchester census-designated place...

 as New Hampshire Route 78

New Hampshire Route 78

New Hampshire Route 78 is a long secondary north–south state highway in Cheshire County in the southern part of the U.S. state of New Hampshire. It runs from the Massachusetts border to Winchester....

. The route does not intersect any other state routes.