Route 143 is a 24.5 mile, 39.4 kilometer west–east state highway

State highway

State highway, state road or state route can refer to one of three related concepts, two of them related to a state or provincial government in a country that is divided into states or provinces :#A...

 in the U.S. state

U.S. state

A U.S. state is any one of the 50 federated states of the United States of America that share sovereignty with the federal government. Because of this shared sovereignty, an American is a citizen both of the federal entity and of his or her state of domicile. Four states use the official title of...

 of Massachusetts

Massachusetts

The Commonwealth of Massachusetts is a state in the New England region of the northeastern United States of America. It is bordered by Rhode Island and Connecticut to the south, New York to the west, and Vermont and New Hampshire to the north; at its east lies the Atlantic Ocean. As of the 2010...

. Its western terminus is at Route 8 in Hinsdale

Hinsdale, Massachusetts

Hinsdale is a town in Berkshire County, Massachusetts, United States. It is part of the Pittsfield, Massachusetts Metropolitan Statistical Area...

, at the town's center. Its eastern terminus is at Route 9 near the village of Searsville in Williamsburg

Williamsburg, Massachusetts

Williamsburg is a town in Hampshire County, Massachusetts, United States. The population was 2,482 at the 2010 census. It is part of the Springfield, Massachusetts Metropolitan Statistical Area.-The Mill River Flood:...

. At Worthington

Worthington, Massachusetts

Worthington is a town in Hampshire County, Massachusetts, United States. The population was 1,270 at the 2000 census. It is part of the Springfield, Massachusetts Metropolitan Statistical Area.-Geography:...

, the highway runs concurrently with Route 112 for 0.8 miles (1.29 km), beginning at Worthington Corners. The road is also the only state route through the towns of Peru

Peru, Massachusetts

Peru is a town in Berkshire County, Massachusetts, United States. The population was 821 at the 2000 census.- History :Originally known as Northern Berkshire Township Number 2 and including all of Hinsdale and part of Middlefield, the town was first settled in 1767 and was officially incorporated...

 and Chesterfield

Chesterfield, Massachusetts

Chesterfield is a rural hill town in Hampshire County, Massachusetts, United States, 28 miles southeast of Pittsfield and 108 miles west of Boston. The population was 1,201 at the 2000 census. It is part of the Springfield, Massachusetts Metropolitan Statistical Area.-History:Chesterfield was...

, and also crosses the Westfield River

Westfield River

The Westfield River in Metropolitan Springfield, Massachusetts, is a major tributary of the Connecticut River in Hampden County, Massachusetts. The Westfield River has four major tributary branches that confluence in the City of Westfield, for which the river is named...

in Chesterfield.

History

Route 143 was originally numbered Route 109A in 1930. The route was renumbered to 143 by 1933.