Martin Kreitman
Encyclopedia
Martin Kreitman is an American geneticist
Geneticist
A geneticist is a biologist who studies genetics, the science of genes, heredity, and variation of organisms. A geneticist can be employed as a researcher or lecturer. Some geneticists perform experiments and analyze data to interpret the inheritance of skills. A geneticist is also a Consultant or...

, and Professor at the University of Chicago
University of Chicago
The University of Chicago is a private research university in Chicago, Illinois, USA. It was founded by the American Baptist Education Society with a donation from oil magnate and philanthropist John D. Rockefeller and incorporated in 1890...

.

He graduated from Stony Brook University with a B.S. Biology, in 1975, and from University of Florida
University of Florida
The University of Florida is an American public land-grant, sea-grant, and space-grant research university located on a campus in Gainesville, Florida. The university traces its historical origins to 1853, and has operated continuously on its present Gainesville campus since September 1906...

 with a M.S. Zoology, in 1977, and from Harvard University
Harvard University
Harvard University is a private Ivy League university located in Cambridge, Massachusetts, United States, established in 1636 by the Massachusetts legislature. Harvard is the oldest institution of higher learning in the United States and the first corporation chartered in the country...

 with a Ph.D. in Population Genetics, in 1983.

Awards

  • 1991 MacArthur Fellows Program
    MacArthur Fellows Program
    The MacArthur Fellows Program or MacArthur Fellowship is an award given by the John D. and Catherine T...

  • editor-in-chief of "Journal of Molecular Evolution" from 1999
  • Section head of the "Evolutionary/Comparative Genetics" part of Faculty of 1000 biology
  • 2010 named fellow of the American Academy of Arts and Sciences

Important publications

  • "Nucleotide polymorphism at the alcohol dehydrogenase locus of Drosophila melanogaster". M Kreitman - Nature, 1983
  • "Adaptive protein evolution at the Adh locus in Drosophila". JH McDonald, M Kreitman - Nature, 1991
  • "A test of neutral molecular evolution based on nucleotide data". RR Hudson, M Kreitman, M Aguadé - Genetics, 1987
  • "Methods to Detect Selection in Populations with Applications to the Human". M Kreitman - Annual Review of Genomics and Human Genetics, 2000 (a good review)

Recent Publications

  • He, B. Z., Holloway, A. K., Maerkl, S. J. & Kreitman, M. 2011 "Does positive selection drive transcription factor binding site turnover? a test with drosophila Cis-Regulatory modules." PLoS Genet 7(4) e1002053+
  • Lott, S.E., Ludwig M.Z., Kreitman M. "Evolution And Inheritance of Early Embryonic Patterning in Drosophila simulans AND D. sechellia." Evolution
  • Bakker, E.G., Traw M.B., Toomajian C., Kreitman M. and J. Bergelson 2008. "Low levels of polymorphism in genes that control the activation of defense response in Arabidopsis thaliana". Genetics 178:2031-43.
  • Araki, H., H. Innan, M. Kreitman and J. Bergelson 2007. "Molecular evolution of pathogenicity-island genes in Pleudomonal viridiflava". Genetics 177:1031-41.
  • Lott, S.E., Kreitman, M., Palsson A., Alekseeva, E. and M.Z. Ludwig 2007. "Canalization of segmentation and its evolution in Drosophila". Proc. Natl. Acad. Sci. U.S.A. 104:10926-31.
  • Bakker EG, Toomajian C, Kreitman M, and J Bergelson. "A genome-wide survey of R gene polymorphisms in Arabidopsis". Plant Cell 18:1803-18.
  • Bakker E.G., Stahl, E.A., Toomajian, C. Nordborg, M., Kreitman, M. and J.M Bergelson 2006. "Distribution of genetic variation within and among local populations of Arabidopsis thaliana over its species range". Mol Ecol. 15:1405-18.
  • Araki, H., D. Tian, E.M. Goss, K. Jakob, S.S. Halldosdottir, M. Kreitman and J. Bergelson 2006. "Presence/absence polymorphism for alternative pathogenicity islands inPseudomonas viridiflava, a pathogen of Arabidopsis". Proc. Natl. Acad. Sci. USA 103:5887-92.
  • Nordborg, M., T.T. Hu, Y. Ishino, J. Jhaveri, C. Toomajian, H. Zheng, E. Bakker, P. Calabrese, J. Gladstone, R. Goyal, M. Jabobsson, S. Kim, Y. Morozov, B. Padhudasahasram, V. Plagnol, N.A. Rosenberg, C. Shah, J. Wall, J. Wang, K. Zhao, T. Kalbfleisch, V. Schulz, M. Kreitman, J. Bergelson. 2005 "The pattern of polymorphism in Arabidopsis thaliana". PloS Biology 3(7) e196.
  • Ludwig, M., A. Palsson, C. Bergman, E. Alekseeva, J. Nathan and M. Kreitman 2005. "Functional evolution of a cis-regulatory module". PloS Biology 3:588-98.
  • Kreitman, M. and A. Di Rienzo 2004. "Balancing claims for balancing selection". Trends Genet. 20:300-304.
  • Goss, E.M., M. Kreitman and J. Bergelson 2005 "Genetic diversity, recombination and cryptic clades of Pseudomonas viridiflava populations of Arabidopsis thaliana". Genetics 169:23-35.
  • Mauricio, R., E.A. Stahl, T. Korves, D. Tian, M. Kreitman and J. Bergelson 2003. "natural selection for polymorphism in the disease resistance gene Rps2 of Arabidopsis thaliana". Genetics 163:735-46.
  • Tian, D., M.B. Traw, J.Q. Chen, M. Kreitman and J. Bergelson 2003. "Fitness costs of R-gene-mediated resistance in Arabidopsis thaliana". Nature 423:74-7.
  • Toomajian, C., R.S. Ajioka, L.B. Jorde, J.P. Kushner and M. Kreitman 2003. "A method for detecting recent selection in the human genome from allele age estimates". Genetics 165:287-97.
  • Tian, D, H. araki, E. Stahl, J. Bergelson and M. Kreitman 2002. "Signature of balancing selection in Arabidopsis". Proc. Natl. Acad. Sci. USA 99:11525-30.
  • Toomanian, C. and M. Kreitman 2002. "Sequence variation and haplotype structure at the human HFE locus". Genetics 161:1609-23.
  • Jakob K. E. M. Gos, H. Araki, T. Van, M. Kreitman and J. Bergelson 2002. "Pseudomonas viridiflava and P. syringae – natural pathogens of Arabidopsis thaliana". Mol Plant Microbe Interact. 15: 1195-203.
  • Comeron, J. and M. Kreitman 2002. "Population, evolutionary and genomic consequences of Iintereference selection". Genetics 161:389-410.
  • Nordborg M., J. O. Borevitz, J. Bergelson, C. C. Berry, J. Chory, J. Hagenblad, M. Kreitman, J. N. Maloof, T. Noyes, P. J. Oefner, E. A. Stahl and D. Weigel 2002. "The extent of linkage disequilibrium in Arabidopsis thaliana". Nat Genet. 30:190-193.
  • Bergman, C.M. and M. Kreitman 2001. "Analysis of conserved noncoding DNA in Drosophila reveals similar constraints in intergenic and intronic sequences". Genome Res. 11(8):1335-45.
  • Bergelson, J. M. Kreitman, E. A. Stahl and D. Tian 2001. "Evolutionary dynamics of plant R-genes". Science 292:2281-2285.
  • Comeron, J. and M. Kreitman 2000. "The correlation between intron length and recombination in Drosophila: Dynamic equilibrium between mutation and selective forces". Genetics 156:1175-1190.
  • Ludwig, M.Z, C. Bergman, N.H. Patel and M. Kreitman 2000. "Functional evidence for stabilizing selection in a eukaryotic cis-regulatory element". Nature 403:564-567.
  • Stahl, E. A., J. Bergelson, G. Dwyer, R. Mauricio and M. Kreitman 1999. "Dynamics of disease resistance polymorphism at the Rpm1 locus of Arabidiposis". Nature 400:667-671.
  • Comeron, J. and M. Kreitman, and M. Aguade 1999. "Natural selection on synonymous sites is correlated with gene length and recombination rate in Drosophila". Genetics 151(1):239-49.
  • Ludwig, M., N. Patel, and M. Kreitman 1998. "Functional conservation of even-skipped stripe 2 enhancer in Drosophila". Development 125:949-958.

External links

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