Macrodomain
Encyclopedia
The Escherichia coli
chromosome shows two main levels of global organization, macrodomains and replichore
s. Macrodomains were discovered by cytological studies. They contain loci showing the same intracellular positioning and choreography during the cell cycle.
Escherichia coli
Escherichia coli is a Gram-negative, rod-shaped bacterium that is commonly found in the lower intestine of warm-blooded organisms . Most E. coli strains are harmless, but some serotypes can cause serious food poisoning in humans, and are occasionally responsible for product recalls...
chromosome shows two main levels of global organization, macrodomains and replichore
Replichore
The Escherichia coli chromosome shows two main levels of global organization, macrodomains and replichores. In E. coli chromosomes, the origin and terminus of replication divide the genome into oppositely replicated halves called replichores. Replichore 1, which is replicated clockwise, has the...
s. Macrodomains were discovered by cytological studies. They contain loci showing the same intracellular positioning and choreography during the cell cycle.