Macrencephaly
Encyclopedia
Macrencephaly is a condition present at or soon after birth
Childbirth
Childbirth is the culmination of a human pregnancy or gestation period with the birth of one or more newborn infants from a woman's uterus...

 in which the brain is abnormally large. Generally this is the case when its measures are statistically more than 97% of the population.

The brain can become larger due to certain diseases like Alexander disease
Alexander disease
Alexander disease is a slowly progressing and fatal neurodegenerative disease. It is a very rare disorder which results from a genetic mutation and mostly affects infants and children, causing developmental delay and changes in physical characteristics....

, later phases of the Tay-Sachs disease
Tay-Sachs disease
Tay–Sachs disease is an autosomal recessive genetic disorder...

, and spongy degeneration of infancy. The large growth of the brain is usually not caused by the formation of tumor
Tumor
A tumor or tumour is commonly used as a synonym for a neoplasm that appears enlarged in size. Tumor is not synonymous with cancer...

s.

Macrencephaly is also known as macrencephalia and macroencephaly.

See also: cephalic disorders.
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