MYLK3
Encyclopedia
Myosin light chain kinase 3 also known as MYLK3, is an enzyme
which in humans is encoded by the MYLK3 gene
.
of cardiac myosin
heavy chains (see MYH7B
) and light chains (see MYL2
) by a kinase
, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocyte
s.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
which in humans is encoded by the MYLK3 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Function
PhosphorylationPhosphorylation
Phosphorylation is the addition of a phosphate group to a protein or other organic molecule. Phosphorylation activates or deactivates many protein enzymes....
of cardiac myosin
Myosin
Myosins comprise a family of ATP-dependent motor proteins and are best known for their role in muscle contraction and their involvement in a wide range of other eukaryotic motility processes. They are responsible for actin-based motility. The term was originally used to describe a group of similar...
heavy chains (see MYH7B
MYH7B
Myosin-7B also known as myosin, heavy chain 7B is a protein that in humans is encoded by the MYH7B gene....
) and light chains (see MYL2
MYL2
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform is a protein that in humans is encoded by the MYL2 gene.- External links :* * Info with links in the...
) by a kinase
Kinase
In chemistry and biochemistry, a kinase is a type of enzyme that transfers phosphate groups from high-energy donor molecules, such as ATP, to specific substrates, a process referred to as phosphorylation. Kinases are part of the larger family of phosphotransferases...
, such as MYLK3, potentiates the force and rate of cross-bridge recruitment in cardiac myocyte
Myocyte
A myocyte is the type of cell found in muscles. They arise from myoblasts.Each myocyte contains myofibrils, which are long, long chains of sarcomeres, the contractile units of the cell....
s.