MOCOS
Encyclopedia
Molybdenum cofactor sulfurase is an enzyme
that in humans is encoded by the MOCOS gene
.
MOCOS sulfurates the molybdenum cofactor of xanthine dehydrogenase (XDH
) and aldehyde oxidase (AOX1
), which is required for their enzymatic activities.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the MOCOS gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
MOCOS sulfurates the molybdenum cofactor of xanthine dehydrogenase (XDH
Xanthine dehydrogenase
Xanthine dehydrogenase, also known as XDH, is a protein that, in humans, is encoded by the XDH gene.-Function:Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer...
) and aldehyde oxidase (AOX1
Aldehyde oxidase 1
Aldehyde oxidase 1 is an enzyme that in humans is encoded by the AOX1 gene.Aldehyde oxidase produces hydrogen peroxide and, under certain conditions, can catalyze the formation of superoxide.- Clinical significance :...
), which is required for their enzymatic activities.