MINDO, or Modified Intermediate Neglect of Differential Overlap is a semi-empirical method for the quantum

Quantum mechanics

Quantum mechanics, also known as quantum physics or quantum theory, is a branch of physics providing a mathematical description of much of the dual particle-like and wave-like behavior and interactions of energy and matter. It departs from classical mechanics primarily at the atomic and subatomic...

 calculation of molecular electronic structure in computational chemistry

Computational chemistry

Computational chemistry is a branch of chemistry that uses principles of computer science to assist in solving chemical problems. It uses the results of theoretical chemistry, incorporated into efficient computer programs, to calculate the structures and properties of molecules and solids...

. It is based on the Intermediate Neglect of Differential Overlap (INDO

INDO

INDO stands for Intermediate Neglect of Differential Overlap. It is a semi-empirical quantum chemistry method that is a development of the complete neglect of differential overlap method introduced by John Pople...

) method of John Pople

John Pople

Sir John Anthony Pople, KBE, FRS, was a Nobel-Prize winning theoretical chemist. Born in Burnham-on-Sea, Somerset, England, he attended Bristol Grammar School. He won a scholarship to Trinity College, Cambridge in 1943. He received his B. A. in 1946. Between 1945 and 1947 he worked at the Bristol...

. It was developed by the group of Michael Dewar and was the original method in the MOPAC

MOPAC

In computational chemistry, MOPAC is a popular computer program designed to implement semi-empirical quantum chemistry algorithms, such as MINDO, MNDO, AM1, PM3, PM5, and . It was largely written in the group of Michael Dewar at University of Texas, Austin...

 program. The method should actually be referred to as MINDO/3. It was later replaced by the MNDO

MNDO

MNDO, or Modified Neglect of Differential Overlap is a semi-empirical method for the quantum calculation of molecular electronic structure in computational chemistry. It is based on the Neglect of Differential Diatomic Overlap integral approximation. Similarly, this method replaced the earlier...

 method, which in turn was replaced by the PM3

PM3 (chemistry)

PM3, or Parameterized Model number 3, is a semi-empirical method for the quantum calculation of molecular electronic structure in computational chemistry. It is based on the Neglect of Differential Diatomic Overlap integral approximation....

 and AM1 methods.