MED21
Encyclopedia
Mediator of RNA polymerase II transcription subunit 21 is an enzyme
that in humans is encoded by the MED21 gene
.
with Cyclin-dependent kinase 8
, BRCA1
, GTF2H4
, MED6
, POLR2A
and GTF2F1
.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the MED21 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
MED21 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with Cyclin-dependent kinase 8
Cyclin-dependent kinase 8
Cell division protein kinase 8 is an enzyme that in humans is encoded by the CDK8 gene.-Interactions:Cyclin-dependent kinase 8 has been shown to interact with MED16, MED26, MED17, MED14, CREB binding protein, MED1, MED6, MED24, CCNC, POLR2A, MED21, SMARCB1, MED12 and CRSP3....
, BRCA1
BRCA1
BRCA1 is a human caretaker gene that produces a protein called breast cancer type 1 susceptibility protein, responsible for repairing DNA. The first evidence for the existence of the gene was provided by the King laboratory at UC Berkeley in 1990...
, GTF2H4
GTF2H4
General transcription factor IIH subunit 4 is a protein that in humans is encoded by the GTF2H4 gene.-Interactions:GTF2H4 has been shown to interact with MED21, GTF2F1, TATA binding protein, XPB, POLR2A and Transcription Factor II B....
, MED6
MED6
Mediator of RNA polymerase II transcription subunit 6 is an enzyme that in humans is encoded by the MED6 gene.-Interactions:MED6 has been shown to interact with Thyroid hormone receptor alpha, Estrogen receptor alpha, MED21 and Cyclin-dependent kinase 8.-Further reading:...
, POLR2A
POLR2A
DNA-directed RNA polymerase II subunit RPB1 is an enzyme that in humans is encoded by the POLR2A gene.-Interactions:POLR2A has been shown to interact with Transcription elongation regulator 1, CREB-binding protein, BRCA1, GTF2H4, TATA-binding protein, PCAF, GTF2F1, SUPT5H, Transcription Factor II...
and GTF2F1
GTF2F1
General transcription factor IIF subunit 1 is a protein that in humans is encoded by the GTF2F1 gene.-Interactions:GTF2F1 has been shown to interact with TAF1, HNRPU, GTF2H4, CTDP1, TATA binding protein, POLR2A, MED21, TAF11, Serum response factor and Transcription Factor II B.-Further reading:...
.