MAPK3
Encyclopedia
Mitogen-activated protein kinase 3 is an enzyme
that in humans is encoded by the MAPK3 gene
.
with PTPN7
, SPIB
, GTF2I
, DUSP3
, HDAC4
, RPS6KA2
, MAP2K1
, DUSP6
and MAP2K2
.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the MAPK3 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
Interactions
MAPK3 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with PTPN7
PTPN7
Protein tyrosine phosphatase non-receptor type 7 is an enzyme that in humans is encoded by the PTPN7 gene.-Interactions:PTPN7 has been shown to interact with MAPK3 and MAPK1.-Further reading:...
, SPIB
SPIB
Transcription factor Spi-B is a protein that in humans is encoded by the SPIB gene.-Interactions:SPIB has been shown to interact with MAPK3 and MAPK8....
, GTF2I
GTF2I
General transcription factor II-I is a protein that in humans is encoded by the GTF2I gene.-Interactions:GTF2I has been shown to interact with USF1 , Histone deacetylase 2, PRKG1, Myc, MAPK3, HDAC3, Serum response factor and Bruton's tyrosine kinase.-Further reading:...
, DUSP3
DUSP3
Dual specificity protein phosphatase 3 is an enzyme that in humans is encoded by the DUSP3 gene.-Interactions:DUSP3 has been shown to interact with MAPK3 and MAPK1.-Further reading:...
, HDAC4
HDAC4
Histone deacetylase 4, also known as HDAC4, is a protein which in humans is encoded by the HDAC4 gene.- Function :Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects...
, RPS6KA2
RPS6KA2
Ribosomal protein S6 kinase alpha-2 is an enzyme that in humans is encoded by the RPS6KA2 gene.-Interactions:RPS6KA2 has been shown to interact with MAPK3 and MAPK1.-Further reading:...
, MAP2K1
MAP2K1
Dual specificity mitogen-activated protein kinase kinase 1 is an enzyme that in humans is encoded by the MAP2K1 gene.- Function :The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein kinase kinase...
, DUSP6
DUSP6
Dual specificity phosphatase 6, also known as DUSP6, is an enzyme that in humans is encoded by the DUSP6 gene.- Function :The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both...
and MAP2K2
MAP2K2
Dual specificity mitogen-activated protein kinase kinase 2 is an enzyme that in humans is encoded by the MAP2K2 gene.- Function :The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in...
.