The Liverpool and Bury Railway was formed in 1845 and opened on 28 November 1848. The line ran from Liverpool Exchange

Liverpool Exchange railway station

Liverpool Exchange railway station was a railway station located in the town centre of Liverpool, England.- Station construction and opening :...

 first using a joint line with Liverpool, Ormskirk and Preston Railway

Liverpool, Ormskirk and Preston Railway

The Liverpool, Ormskirk & Preston Railway was formed in 1846. It was purchased by the East Lancashire Railway. Today the line still operates, with the section between Liverpool and Ormskirk forming part of Merseyrail's Northern Line and the section between Ormskirk and Preston forming Northern...

 before branching of to proceed via Kirkby

Kirkby

Kirkby is a town in the Metropolitan Borough of Knowsley in the metropolitan county of Merseyside in England. The town was developed from the 1950s through 1970s as a means to house the overspill of Liverpool. It is situated roughly north of Huyton, the administrative HQ of the borough and about...

 then Wigan

Wigan

Wigan is a town in Greater Manchester, England. It stands on the River Douglas, south-west of Bolton, north of Warrington and west-northwest of Manchester. Wigan is the largest settlement in the Metropolitan Borough of Wigan and is its administrative centre. The town of Wigan had a total...

 and Bolton

Bolton

Bolton is a town in Greater Manchester, in the North West of England. Close to the West Pennine Moors, it is north west of the city of Manchester. Bolton is surrounded by several smaller towns and villages which together form the Metropolitan Borough of Bolton, of which Bolton is the...

 to Bury

Bury

Bury is a town in Greater Manchester, England. It lies on the River Irwell, east of Bolton, west-southwest of Rochdale, and north-northwest of the city of Manchester...

.

In 1846 the line merged with the Manchester & Leeds Railway being eventually finished after the merger to form the Lancashire and Yorkshire Railway

Lancashire and Yorkshire Railway

The Lancashire and Yorkshire Railway was a major British railway company before the 1923 Grouping. It was incorporated in 1847 from an amalgamation of several existing railways...

. The line eventually formed part of the Lancashire and Yorkshire Railway

Lancashire and Yorkshire Railway

The Lancashire and Yorkshire Railway was a major British railway company before the 1923 Grouping. It was incorporated in 1847 from an amalgamation of several existing railways...

, 59.5 kilometres (37 mi) Liverpool to Manchester route via a junction with the Manchester and Southport Railway

Manchester and Southport Railway

The Manchester and Southport Railway in England opened on 9 April 1855. It merged with the Lancashire and Yorkshire Railway in January 1885. The line eventually formed part of the Lancashire and Yorkshire Railway, 59.5 km Liverpool to Manchester route via a junction with the Liverpool and Bury...

 at Wigan

Wigan

Wigan is a town in Greater Manchester, England. It stands on the River Douglas, south-west of Bolton, north of Warrington and west-northwest of Manchester. Wigan is the largest settlement in the Metropolitan Borough of Wigan and is its administrative centre. The town of Wigan had a total...

.

From 1858 the line was connected to the Skelmersdale Branch

Skelmersdale Branch

The Skelmersdale Branch railway connected the Liverpool, Ormskirk and Preston Railway at Ormskirk with Rainford Junction . At Rainford it connected with the Liverpool and Bury Railway and the St. Helens Railway. It was built by the East Lancashire Railway, which was taken over by the Lancashire...

 and the St. Helens Railway at Rainford Junction.

With the exception of the section from Bolton to Bury the line is still in use, though Liverpool Exchange station closed in the 1970s being replaced by Liverpool Moorfields

Moorfields railway station

Moorfields station is an underground railway station in Liverpool, England. It is situated on both the Northern and Wirral Lines of the Merseyrail network and is the only station on the network which has services to all other Merseyrail stations....

 in the Link Tunnel.

The line from Liverpool city centre to Kirkby is now electrified with a DC

Direct current

Direct current is the unidirectional flow of electric charge. Direct current is produced by such sources as batteries, thermocouples, solar cells, and commutator-type electric machines of the dynamo type. Direct current may flow in a conductor such as a wire, but can also flow through...

 third rail

Third rail

A third rail is a method of providing electric power to a railway train, through a semi-continuous rigid conductor placed alongside or between the rails of a railway track. It is used typically in a mass transit or rapid transit system, which has alignments in its own corridors, fully or almost...

 forming a part of Merseyrail's Northern Line

Northern Line (Merseyrail)

The Northern Line is one of the two commuter rail lines operated by Merseyrail in Merseyside, England. The other line is the Wirral Line. A third line of the Merseyrail Network, the City Line, is not owned or operated by Merseyrail, although funded by Merseytravel.The Northern Line passes...

. At present, services from Kirkby onwards are operated by diesel trains, however there are plans for the Merseyrail electrified line to be extended towards Wigan with a new terminus at .