Following is a list of persons who have headed the United States Patent Office. The title associated with this function has changed over time, from Superintendent of Patents to Commissioner of Patents to Undersecretary of Commerce for Intellectual Property. The duties of the office have also evolved significantly, including coming to encompass the supervision of trademark issuance as well as that of patents.

Patent Office Head	Began service	Ended service
	1 Jun 1802	28 Mar 1828
	12 Apr 1828	10 Jun 1829
	11 Jun 1829	1 Feb 1835
	1 Feb 1835	May 1835
	8 Jul 1835	1 Apr 1845
	May 4, 1845	1849
	May 9, 1849	1852
	November 8, 1852	1853
	May 16, 1853	5 Aug 1857
	September 10, 1857	Mar 1859
	May 27, 1859	1860
	February 16, 1860	10 Dec 1860
	March 28, 1861	1865
	August 17, 1866	20 Jan 1868
	July 29, 1868	Mar 1869
	April 26, 1869	10 Nov 1870
	January 16, 1871	1874
	November 4, 1874	1 Oct 1875
	October 1, 1875	1877
	January 30, 1877	1878
	November 1, 1878	1880
	May 7, 1880	1883
	November 1, 1883	1885
	March 23, 1885	1887
	April 12, 1887	1889
	April 1, 1889	1891
	August 1, 1891	1892
	March 31, 1893	1897
	April 7, 1897	1898
	February 3, 1898	1901
	April 11, 1901	1907
	1907	1913
	1913	1917
	1917	1920
	1920	1921
	1921	1921
	1921	1933
	1933	14 Sep 1945
	15 Sep 1945	1947
	1947	1949
	1949	1953
	1953	1961
	1961	1963
	1964	1969
	1969	1971
	1972	1973
	1974	1977
	1978	1979
	1979	1981
	1981	1985
	1985	1990
	1990	1992
	5 Aug 1993	1998
	1998	19 Jan 2001
	Jan 2001	29 Mar 2005
	Apr 2005	Nov 2008
	Nov 2008	13 Aug 2009
	13 Aug 2009	5 Oct 2009
	5 Oct 2009	Present

Beginning in 2001, the Patent Office has been under an Undersecretary of Commerce. The persons holding this office have been:

Patent Office Head	Began service	Ended service
	10 Dec 2001	9 Jan 2004
	2004	20 Jan 2009
	20 Jan 2009	13 Aug 2009
	13 Aug 2009	Present