Leptosphaeria maculans
Encyclopedia
Leptosphaeria maculans (anamorph Phoma lingam) is a fungal pathogen that is the causal agent of blackleg
Blackleg
Blackleg may refer to:* Strikebreaker* Card sharp* Appalousa tribe* Operation Blackleg, dive operation on warship HMS Coventry * Blackleg , in sheep and cattle* Scurvy, deficiency in primates & some other animals...

 disease on Brassica
Brassica
Brassica is a genus of plants in the mustard family . The members of the genus may be collectively known either as cabbages, or as mustards...

crops. The major yield loss is due to stem canker
Canker
Canker and anthracnose are general terms for a large number of different plant diseases, characterised by broadly similar symptoms including the appearance of small areas of dead tissue, which grow slowly, often over a period of years. Some are of only minor consequence, but others are ultimately...

.

L. maculans metabolizes brassinin, an important phytoalexin produced by Brassica species, into indole-3-carboxaldehyde and indole-3-carboxylic acid. Virulent isolates proceed through the (3-indolylmethyl)dithiocarbamate S-oxide intermediate, while avirulent isolates first convert brassinin to N-acetyl-3-indolylmethylamine and 3-indolylmethylamine.

As a bioengineering innovation, recently it was shown that a light-driven protein from L. maculans could be used to mediate, alongside earlier reagents, multi-color silencing of neurons in the mammalian nervous system.

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