LATS1
Encyclopedia
Serine/threonine-protein kinase LATS1 is an enzyme
that in humans is encoded by the LATS1 gene
.
It has been associated with the Hippo signaling pathway
.
with Zyxin
and Cdk1
.
Enzyme
Enzymes are proteins that catalyze chemical reactions. In enzymatic reactions, the molecules at the beginning of the process, called substrates, are converted into different molecules, called products. Almost all chemical reactions in a biological cell need enzymes in order to occur at rates...
that in humans is encoded by the LATS1 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
.
It has been associated with the Hippo signaling pathway
Hippo signaling pathway
The Hippo signaling pathway, also known as the Salvador/Warts/Hippo pathway, controls organ size in animals through the regulation of cell proliferation and apoptosis. The pathway takes its name from one of its key signaling components—the protein kinase Hippo...
.
Interactions
LATS1 has been shown to interactProtein-protein interaction
Protein–protein interactions occur when two or more proteins bind together, often to carry out their biological function. Many of the most important molecular processes in the cell such as DNA replication are carried out by large molecular machines that are built from a large number of protein...
with Zyxin
Zyxin
Zyxin is a protein that in humans is encoded by the ZYX gene.-Interactions:Zyxin has been shown to interact with ENAH, LASP1, LATS1, Actinin, alpha 1 and Vasodilator-stimulated phosphoprotein.-External links:* Info with links in the...
and Cdk1
Cdk1
Cyclin dependent kinase 1 also known as Cdk1 or cell division control protein 2 homolog is a highly conserved protein that functions as a serine/threonine kinase, and is a key player in cell cycle regulation. It has been highly studied in the budding yeast S. cerevisiae, and the fission yeast S....
.