Ki Database
Encyclopedia
The Ki Database is a public domain
database
of published binding affinities
(Ki) of drugs
and chemical compound
s for receptors
, neurotransmitter transporter
s, ion channel
s, and enzymes. The resource is maintained by the University of North Carolina at Chapel Hill
and is funded by the NIMH
Psychoactive Drug Screening Program and by a gift from the Heffter Research Institute
. As of April,2010, the database has data for 7449 compounds at 738 different receptors.
Public domain
Works are in the public domain if the intellectual property rights have expired, if the intellectual property rights are forfeited, or if they are not covered by intellectual property rights at all...
database
Database
A database is an organized collection of data for one or more purposes, usually in digital form. The data are typically organized to model relevant aspects of reality , in a way that supports processes requiring this information...
of published binding affinities
Dissociation constant
In chemistry, biochemistry, and pharmacology, a dissociation constant is a specific type of equilibrium constant that measures the propensity of a larger object to separate reversibly into smaller components, as when a complex falls apart into its component molecules, or when a salt splits up into...
(Ki) of drugs
DRUGS
Destroy Rebuild Until God Shows are an American post-hardcore band formed in 2010. They released their debut self-titled album on February 22, 2011.- Formation :...
and chemical compound
Chemical compound
A chemical compound is a pure chemical substance consisting of two or more different chemical elements that can be separated into simpler substances by chemical reactions. Chemical compounds have a unique and defined chemical structure; they consist of a fixed ratio of atoms that are held together...
s for receptors
Receptor (biochemistry)
In biochemistry, a receptor is a molecule found on the surface of a cell, which receives specific chemical signals from neighbouring cells or the wider environment within an organism...
, neurotransmitter transporter
Neurotransmitter transporter
Neurotransmitter transporters are a class of membrane transport proteins that span the cellular membranes of neurons. Their primary function is to carry neurotransmitters across these membranes and to direct their further transport to specific intracellular locations...
s, ion channel
Ion channel
Ion channels are pore-forming proteins that help establish and control the small voltage gradient across the plasma membrane of cells by allowing the flow of ions down their electrochemical gradient. They are present in the membranes that surround all biological cells...
s, and enzymes. The resource is maintained by the University of North Carolina at Chapel Hill
University of North Carolina at Chapel Hill
The University of North Carolina at Chapel Hill is a public research university located in Chapel Hill, North Carolina, United States...
and is funded by the NIMH
National Institute of Mental Health
The National Institute of Mental Health is one of 27 institutes and centers that make up the National Institutes of Health...
Psychoactive Drug Screening Program and by a gift from the Heffter Research Institute
Heffter Research Institute
The Heffter Research Institute was incorporated in New Mexico in 1993 as a non-profit organization to support and promote investigation into the medical uses of psychedelic hallucinogens...
. As of April,2010, the database has data for 7449 compounds at 738 different receptors.