John Bosley Ziegler
Encyclopedia
John Bosley Ziegler, John Ziegler, Montana Jack, (circa 1920 - 1983) was an American physician
Physician
A physician is a health care provider who practices the profession of medicine, which is concerned with promoting, maintaining or restoring human health through the study, diagnosis, and treatment of disease, injury and other physical and mental impairments...

 who originally developed the anabolic steroid
Anabolic steroid
Anabolic steroids, technically known as anabolic-androgen steroids or colloquially simply as "steroids", are drugs that mimic the effects of testosterone and dihydrotestosterone in the body. They increase protein synthesis within cells, which results in the buildup of cellular tissue ,...

 Methandrostenolone
Methandrostenolone
Methandrostenolone is an orally-effective anabolic steroid originally developed by John Ziegler and released in the US in the early 1960s by Ciba. It was used as an aid to muscle growth by bodybuilders until its ban by Congress under the Controlled Substances Act...

 (Dianabol, DBOL) which was released in the USA in 1958 by Ciba
Ciba Specialty Chemicals
Ciba was a chemical company based in and near Basel, Switzerland. "Ciba" stood for "Chemische Industrie Basel" . It was formed as the non-pharmaceuticals elements of Novartis were spun out in 1997, following the merger in the previous year of Ciba-Geigy and Sandoz that created Novartis.In 2008,...

. He pioneered its athletic use as an aid to muscle growth by bodybuilders
Bodybuilding
Bodybuilding is a form of body modification involving intensive muscle hypertrophy. An individual who engages in this activity is referred to as a bodybuilder. In competitive and professional bodybuilding, bodybuilders display their physiques to a panel of judges, who assign points based on their...

, administering it to U.S. weightlifting champion Bill March of the York Barbell club in 1959 when he was the physician to the U.S. Weightlifting team. It was banned by the Food and Drug Administration
Food and Drug Administration
The Food and Drug Administration is an agency of the United States Department of Health and Human Services, one of the United States federal executive departments...

 (FDA) under the Controlled Substances Act
Controlled Substances Act
The Controlled Substances Act was enacted into law by the Congress of the United States as Title II of the Comprehensive Drug Abuse Prevention and Control Act of 1970. The CSA is the federal U.S. drug policy under which the manufacture, importation, possession, use and distribution of certain...

. In later life he was outspoken against its use in sport, saying "It is bad enough to have to deal with drug addicts, but now healthy athletes are putting themselves in the same category. It's a disgrace. Who plays sports for fun anymore?". Ziegler suffered from heart disease
Heart disease
Heart disease, cardiac disease or cardiopathy is an umbrella term for a variety of diseases affecting the heart. , it is the leading cause of death in the United States, England, Canada and Wales, accounting for 25.4% of the total deaths in the United States.-Types:-Coronary heart disease:Coronary...

, which he partially ascribed to his experimentation with steroids, and he died from heart failure in 1983.

Early life

John Ziegler was born in the Midwestern United States
Midwestern United States
The Midwestern United States is one of the four U.S. geographic regions defined by the United States Census Bureau, providing an official definition of the American Midwest....

 but he returned to his family roots in southern Pennsylvania
Pennsylvania
The Commonwealth of Pennsylvania is a U.S. state that is located in the Northeastern and Mid-Atlantic regions of the United States. The state borders Delaware and Maryland to the south, West Virginia to the southwest, Ohio to the west, New York and Ontario, Canada, to the north, and New Jersey to...

 and graduated from Gettysburg College
Gettysburg College
Gettysburg College is a private four-year liberal arts college founded in 1832, in Gettysburg, Pennsylvania, United States, adjacent to the famous battlefield. Its athletic teams are nicknamed the Bullets. Gettysburg College has about 2,700 students, with roughly equal numbers of men and women...

 in 1942. He was descended from three generations of doctors going back to the American Civil War
American Civil War
The American Civil War was a civil war fought in the United States of America. In response to the election of Abraham Lincoln as President of the United States, 11 southern slave states declared their secession from the United States and formed the Confederate States of America ; the other 25...

, and his father had been both practicing physician and a scientist who had discovered the salt tablet.

He served as an officer in the United States Marine Corps
United States Marine Corps
The United States Marine Corps is a branch of the United States Armed Forces responsible for providing power projection from the sea, using the mobility of the United States Navy to deliver combined-arms task forces rapidly. It is one of seven uniformed services of the United States...

 in the Pacific in World War II
World War II
World War II, or the Second World War , was a global conflict lasting from 1939 to 1945, involving most of the world's nations—including all of the great powers—eventually forming two opposing military alliances: the Allies and the Axis...

, where he suffered extensive bullet wounds. His experience of surgery and convalescence lead to a speciality in recuperative medicine at the University of Maryland Medical School. He served his internship and residency at Marine hospitals in Norfolk
Norfolk, Virginia
Norfolk is an independent city in the Commonwealth of Virginia in the United States. With a population of 242,803 as of the 2010 Census, it is Virginia's second-largest city behind neighboring Virginia Beach....

 Virginia
Virginia
The Commonwealth of Virginia , is a U.S. state on the Atlantic Coast of the Southern United States. Virginia is nicknamed the "Old Dominion" and sometimes the "Mother of Presidents" after the eight U.S. presidents born there...

 and Mobile
Mobile, Alabama
Mobile is the third most populous city in the Southern US state of Alabama and is the county seat of Mobile County. It is located on the Mobile River and the central Gulf Coast of the United States. The population within the city limits was 195,111 during the 2010 census. It is the largest...

 Alabama
Alabama
Alabama is a state located in the southeastern region of the United States. It is bordered by Tennessee to the north, Georgia to the east, Florida and the Gulf of Mexico to the south, and Mississippi to the west. Alabama ranks 30th in total land area and ranks second in the size of its inland...

, before completing a two year residence in neurology
Neurology
Neurology is a medical specialty dealing with disorders of the nervous system. Specifically, it deals with the diagnosis and treatment of all categories of disease involving the central, peripheral, and autonomic nervous systems, including their coverings, blood vessels, and all effector tissue,...

 at Tulane University School of Medicine
Tulane University
Tulane University is a private, nonsectarian research university located in New Orleans, Louisiana, United States...

 in New Orleans. In 1954 after he settled in Olney
Olney, Maryland
Olney, a census-designated place and an unincorporated area of Montgomery County, Maryland, USA, is located in the north central part of the county, twenty miles north of Washington, D.C. It was largely agricultural until the 1960s, when growth of the Washington suburbs led to its conversion into...

, Maryland
Maryland
Maryland is a U.S. state located in the Mid Atlantic region of the United States, bordering Virginia, West Virginia, and the District of Columbia to its south and west; Pennsylvania to its north; and Delaware to its east...

 he specialized in the treatment of handicapped and seriously injured patients whilst conducting chemistry research at Ciba Pharmaceuticals part time.

He became an enthusiastic weightlifter who pumped iron at the York
York, Pennsylvania
York, known as the White Rose City , is a city located in York County, Pennsylvania, United States which is in the South Central region of the state. The population within the city limits was 43,718 at the 2010 census, which was a 7.0% increase from the 2000 count of 40,862...

 Barbell Club, which was at the center of American fitness training thanks to its owner Bob Hoffman
Bob Hoffman
Wayne Robert Hoffman was a U.S. American football running back in the NFL for the Washington Redskins and Los Angeles Rams. He also played in the All-America Football Conference for the Los Angeles Dons and in the Pacific Coast Professional Football League for the Hollywood Bears...

. Hoffman had competed with Joe Weider
Joe Weider
Josef E. "Joe" Weider is co-founder of the International Federation of BodyBuilders along with brother Ben Weider and creator of the Mr. Olympia, the Ms. Olympia, and the now-defunct Masters Olympia bodybuilding contests...

 and Charles Atlas
Charles Atlas
Charles Atlas, born Angelo Siciliano , was the developer of a bodybuilding method and its associated exercise program that was best known for a landmark advertising campaign featuring Atlas's name and likeness; it has been described as one of the longest-lasting and most memorable ad campaigns of all...

 for the title of Mr America
AAU Mr. America
AAU Mr. America was a bodybuilding competition started by the Amateur Athletic Union . It was first held on 4 July 1939 and the winner was named "America's Best Built Man". In 1940 this was changed to what is now known as the Mr. America contest....

 and wrote the book Weight Lifting in 1939. Ziegler's scientific credentials supplemented Hoffman's bodybuilding theories. Ziegler befriended weightlifter and bodybuilder champion John Grimek
John Grimek
John Carroll Grimek is recognized as one of the world's greatest bodybuilders and weight lifters of the 1930s and 1940s.Grimek was born on June 17, 1910 in Perth Amboy, New Jersey, son of Slovak immigrants George and Maria Grimek.Besides his bodybuilding exploits, in which he was never defeated,...

 who was employed by Hoffman.

Developing anabolic steroids

Working at CIBA allowed Ziegler access to books and records from Germany where experiments with testosterone had been carried out by the Nazis, and which had been confiscated by the United States after the war.

In October 1954, Ziegler, went to Vienna
Vienna
Vienna is the capital and largest city of the Republic of Austria and one of the nine states of Austria. Vienna is Austria's primary city, with a population of about 1.723 million , and is by far the largest city in Austria, as well as its cultural, economic, and political centre...

 with the American weightlifting team. There he met a Russian physicist who, over "a few drinks", repeatedly asked "What are you giving your boys?" When Ziegler returned the question, the Russian said that his own athletes were being given testosterone. Returning to America, Ziegler tried weak doses of testosterone on himself, on the American trainer Bob Hoffman and on three lifters, John Grimek, Jim Park and Yaz Kuzahara. All gained more weight and strength than any training programme would produce but there were side-effects. Ziegler sought a drug without after-effects and hit on an anabolic steroid, methandrostenolone, (Dianabol, DBOL), made in the U.S. in 1958 by Ciba
Ciba Specialty Chemicals
Ciba was a chemical company based in and near Basel, Switzerland. "Ciba" stood for "Chemische Industrie Basel" . It was formed as the non-pharmaceuticals elements of Novartis were spun out in 1997, following the merger in the previous year of Ciba-Geigy and Sandoz that created Novartis.In 2008,...

.

Ziegler gave Dianabol to the entire U.S. Olympic weightlifting team in Rome in 1960, but they still lost to the Soviets. He gave up experimentation with athletes when he learned that some who had taken 20 times the recommended dose of Dianabol had developed a liver condition. He was quoted in Science
Science (journal)
Science is the academic journal of the American Association for the Advancement of Science and is one of the world's top scientific journals....

saying "I lost interest in fooling with IQ's of that caliber. Now it's about as widespread among these idiots as marihuana." In later years Ziegler regretted introducing AAS to athletes. He recollected "but I wish to God now I’d never done it. I’d like to go back and take that whole chapter out of my life."
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