Jaffe–Campanacci syndrome
Encyclopedia
Jaffe–Campanacci syndrome is one of the disorders associated with café au lait
macules (CALMs). Presentations may include mental retardation
, disseminated non-ossifying fibromas
of the long bones and jaw, hypogonadism
or cryptorchidism
, or giant cell granulomas of the jaw.
It was characterized in 1958 and 1983.
Café au lait
Café au lait is a French coffee drink. The meaning of the term differs between Europe and the United States; in both cases it means some kind of coffee with hot milk added, in contrast to white coffee, which is coffee with room temperature milk or other whitener added.- Europe :In Europe, "café au...
macules (CALMs). Presentations may include mental retardation
Mental retardation
Mental retardation is a generalized disorder appearing before adulthood, characterized by significantly impaired cognitive functioning and deficits in two or more adaptive behaviors...
, disseminated non-ossifying fibromas
Fibroma
Fibromas are benign tumors that are composed of fibrous or connective tissue. They can grow in all organs, arising from mesenchyme tissue. The term "fibroblastic" or "fibromatous" is used to describe tumors of the fibrous connective tissue...
of the long bones and jaw, hypogonadism
Hypogonadism
Hypogonadism is a medical term for decreased functional activity of the gonads. Low testosterone is caused by a decline or deficiency in gonadal production of testosterone in males...
or cryptorchidism
Cryptorchidism
Cryptorchidism is the absence of one or both testes from the scrotum. It is the most common birth defect regarding male genitalia. In unique cases, cryptorchidism can develop later in life, often as late as young adulthood. About 3% of full-term and 30% of premature infant boys are born with at...
, or giant cell granulomas of the jaw.
It was characterized in 1958 and 1983.