Isometheptene
Encyclopedia
Isometheptene is a sympathomimetic amine
Sympathomimetic amine
Sympathomimetic drugs mimic the effects of transmitter substances of the sympathetic nervous system such as catecholamines, epinephrine , norepinephrine , dopamine, etc...

 sometimes used in the treatment of migraine
Migraine
Migraine is a chronic neurological disorder characterized by moderate to severe headaches, and nausea...

s and tension headaches due to its vasoconstricting properties, that is, it causes constriction
Constriction
Constriction is a method used by various snake species to kill their prey. Although some species of venomous and mildly-venomous snakes do use constriction to subdue their prey, most snakes which use constriction lack venom. The snake initially strikes at its prey and holds on, pulling the prey...

 (narrowing) of blood vessel
Blood vessel
The blood vessels are the part of the circulatory system that transports blood throughout the body. There are three major types of blood vessels: the arteries, which carry the blood away from the heart; the capillaries, which enable the actual exchange of water and chemicals between the blood and...

s (arteries and veins). Along with paracetamol
Paracetamol
Paracetamol INN , or acetaminophen USAN , is a widely used over-the-counter analgesic and antipyretic . It is commonly used for the relief of headaches and other minor aches and pains and is a major ingredient in numerous cold and flu remedies...

 and dichloralphenazone
Dichloralphenazone
Dichloralphenazone is a 1:2 mixture of antipyrine with chloral hydrate. In combination with paracetamol and isometheptene, it is the active ingredient of medications for migraine and vascular headaches, including Epidrin and Midrin. Performance impairments are common with this drug and caution is...

, it is one of the constituents of Amidrine
Amidrine
Amidrine, Duradrin, Epidrine, or Midrin, is a combination of acetaminophen, dichloralphenazone, and isometheptene used mostly to treat headaches.-Components:...

.

Chemistry

Isometheptene is a monounsaturated
Saturation (chemistry)
In chemistry, saturation has six different meanings, all based on reaching a maximum capacity...

 aliphatic secondary amine.
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