The Iroquois Theatre fire occurred on December 30, 1903, in Chicago

Chicago

Chicago is the largest city in the US state of Illinois. With nearly 2.7 million residents, it is the most populous city in the Midwestern United States and the third most populous in the US, after New York City and Los Angeles...

, Illinois

Illinois

Illinois is the fifth-most populous state of the United States of America, and is often noted for being a microcosm of the entire country. With Chicago in the northeast, small industrial cities and great agricultural productivity in central and northern Illinois, and natural resources like coal,...

. It is the deadliest theater fire

Fire

Fire is the rapid oxidation of a material in the chemical process of combustion, releasing heat, light, and various reaction products. Slower oxidative processes like rusting or digestion are not included by this definition....

 and the deadliest single-building fire in United States

United States

The United States of America is a federal constitutional republic comprising fifty states and a federal district...

 history. At least 605 people died as a result of the fire but not all the deaths were reported, as some of the bodies were removed from the scene.
The Iroquois Theatre was located at 24–28 West Randolph Street, on the North Side between State Street

State Street (Chicago)

State Street is a large south-north street in Chicago, Illinois, USA and its south suburbs. It begins on the Near North Side at North Avenue. For much of its course, it lies between Wabash Avenue on the east and Dearborn Street/Lafayette Avenue on the west...

 and Dearborn Street in Chicago.