International Neuroinformatics Coordinating Facility
Encyclopedia
The International Neuroinformatics Coordinating Facility (INCF) is an international science organization.
Its purpose is to facilitate worldwide cooperation of activities and infrastructures in neuroinformatics
Neuroinformatics
Neuroinformatics is a research field concerned with the organization of neuroscience data by the application of computational models and analytical tools. These areas of research are important for the integration and analysis of increasingly large-volume, high-dimensional, and fine-grain...

-related fields.
It was established in 2005 by recommendations of the Global Science Forum working group of the OECD. The secretariat is hosted by the Karolinska Institutet
Karolinska Institutet
Karolinska institutet is a medical university in Solna within the Stockholm urban area, Sweden, and one of Europe's largest medical universities...

 in Stockholm
Stockholm
Stockholm is the capital and the largest city of Sweden and constitutes the most populated urban area in Scandinavia. Stockholm is the most populous city in Sweden, with a population of 851,155 in the municipality , 1.37 million in the urban area , and around 2.1 million in the metropolitan area...

, Sweden
Sweden
Sweden , officially the Kingdom of Sweden , is a Nordic country on the Scandinavian Peninsula in Northern Europe. Sweden borders with Norway and Finland and is connected to Denmark by a bridge-tunnel across the Öresund....

. The INCF currently has national nodes in 16 member countries.

Demonstration projects have included the CoCoMac database, NEST
Novell Embedded Systems Technology
Novell Embedded Systems Technology, or NEST, was a series of APIs, data formats and network protocol stacks written in a highly portable fashion intended to be used in embedded systems. The idea was to allow various small devices to access Novell NetWare services, provide such services, or use...

 simulation tool, SumsDB, NeuroScholar, and MUSIC
Multi-simulation coordinator
MUSIC is software developed and released by the INCF and Royal Institute of Technology School of Computer Science and Communication in Stockholm, Sweden. MUSIC allows spike events and continuous time series to be communicated between applications in a cluster computer...

. The INCF also hosts the Neuroscience Peer Review Consortium (NPRC) and INCF Software Center.

The INCF organizes an annual Neuroinformatics Congress; this year's upcoming meeting will be held in Boston
Boston
Boston is the capital of and largest city in Massachusetts, and is one of the oldest cities in the United States. The largest city in New England, Boston is regarded as the unofficial "Capital of New England" for its economic and cultural impact on the entire New England region. The city proper had...

, Massachusetts, at the end of August 2011.
Genesis of the project
The recommendation to coordinate international efforts in the new field of Neuroinformatics was first made in the report on Bioinformatics elaborated under the aegis of the then OECD Megascience Forum in 1998. Following extensive discussions in the Neuroinformatics Working Group of the Global Science Forum chaired by Dr Stephen Koslow, the proposal to create an International Neuroinformatics Coordinating Facility, as well as a funding Programme in International Neuroinformatics (PIN), was then presented in 2002. This project was endorsed by OECD science ministers at their meeting in January 2004. Sixteen countries (Australia, Canada, China, the Czech Republic, Denmark, Finland, France, Germany, India, Italy, Japan, the Netherlands, Norway, Sweden, Switzerland, the United Kingdom and the United States), as well as the European Commission, then elaborated the working documents that form the legal basis for the INCF and the PIN (see below).

Why Neuroinformatics?
A key element to successfully understanding the nervous system is the integration of neuroscience with information sciences. The field that studies the nervous system, neuroscience, has responded to the fantastic challenge of understanding how our brain works with the use of the most sophisticated technologies, from studies on the genome to those on brain imaging of behaviour in humans and other species, under different functional states, and at all intervening analytical levels. This effort has resulted in large quantities of data, which are ever increasing at higher levels of complexity. The data produced are heterogeneous, coming from different levels of study and modalities of analysis. To rise to this challenge of integration, and to ensure efficient and maximum use of these data, it is now necessary to develop and create these shared resources: (i) neuroscience data and knowledge databases; (ii) analytical and modelling tools; and (iii) computational models. This challenge is being met through the merging of neurosciences with information science -- the field of Neuroinformatics.

The establishment process
The conditions laid out for the creation of the INCF were met in July 2005, seven countries (the Czech Republic, Finland, Germany, Norway, Sweden, Switzerland and the United States) having signed the Understanding document and pledged their financial contribution. A bid to host the INCF Secretariat was launched (see related document below). Two proposals were received and, as instructed by the Governing Board, on November 3, the OECD convened a panel of experts to review and rank the proposals. The panel assigned the higher ranking to the Swedish proposal, and this recommendation was endorsed by the INCF Governing Board when it met at OECD headquarters on November 28. Following extensive international discussions, the INCF was officially inaugurated in February 2007, with headquarters at the Karolinska Institute in Stockholm (www.incf.org).
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