The interleukin-18 receptor (IL-18R) is an interleukin receptor

Interleukin receptor

-Types:There are two main families of Interleukin receptors, type 1 and type 2 cytokine receptors.-Other:*Interleukin-1 receptor and interleukin-18 receptor belong to the immunoglobulin superfamily....

 of the immunoglobulin superfamily

Immunoglobulin superfamily

The immunoglobulin superfamily is a large group of cell surface and soluble proteins that are involved in the recognition, binding, or adhesion processes of cells. Molecules are categorized as members of this superfamily based on shared structural features with immunoglobulins ; they all possess a...

. IL-18R is a heteromeric complex of alpha- and beta-chains encoded by the gene

Gene

A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

s and respectively.

Endometrial IL-18 receptor mRNA and the ratio of IL-18 binding protein to interleukin 18 are significantly increased in adenomyosis

Adenomyosis

Adenomyosis is a medical condition characterized by the presence of ectopic glandular tissue found in muscle. The term adenomyosis is derived from the terms adeno- , myo- , and -osis...

patients in comparison to normal people, indicating a role in its pathogenesis.