Ibipinabant is a drug used in scientific research which acts as a potent and highly selective CB₁ antagonist. It has potent anorectic

Anorectic

An anorectic or anorexic , also known as anorexigenic or appetite suppressant, is a dietary supplement and/or drug which reduces appetite, food consumption, and as a result, causes weight loss to occur.-List of anorectics:Numerous pharmaceutical compounds are marketed as appetite suppressants.The...

 effects in animals, and was researched for the treatment of obesity

Obesity

Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have an adverse effect on health, leading to reduced life expectancy and/or increased health problems...

, although CB₁ antagonists as a class have now fallen out of favour as potential anorectics following the problems seen with rimonabant

Rimonabant

Rimonabant is an anorectic antiobesity drug that has been withdrawn from the market. It is an inverse agonist for the cannabinoid receptor CB1...

, and so ibipinabant is now only used for laboratory research, especially structure-activity relationship

Structure-activity relationship

The structure–activity relationship is the relationship between the chemical or 3D structure of a molecule and its biological activity. The analysis of SAR enables the determination of the chemical groups responsible for evoking a target biological effect in the organism...

studies into novel CB₁ antagonists.