Immunoglobulin kappa locus, also known as IGK@, is a region on human chromosome 2 that contains gene

Gene

A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...

s for the kappa (κ) light chains

Immunoglobulin light chain

]The immunoglobulin light chain is the small polypeptide subunit of an antibody .A typical antibody is composed of two immunoglobulin heavy chains and two Ig light chains.-In humans:...

 of antibodies (or immunoglobulins).

In humans the κ chain is coded for by V (variable), J (joining) and C

IGKC

Immunoglobulin kappa constant, also known as IGKC, is a human gene that encodes a the constant domain of kappa-type light chains for antibodies. It is found on chromosome 2, in humans, within the Immunoglobulin kappa locus, IGK@.-Further reading:...

 (constant) genes in this region. These genes undergo V(D)J recombination

V(D)J recombination

VJ recombination, also known as somatic recombination, is a mechanism of genetic recombination in the early stages of immunoglobulin and T cell receptors production of the immune system...

 to generate a diverse repertoire of immunoglobulins.

Genes

The immunoglobulin kappa locus contains the following genes:

• IGKC
  IGKC
  Immunoglobulin kappa constant, also known as IGKC, is a human gene that encodes a the constant domain of kappa-type light chains for antibodies. It is found on chromosome 2, in humans, within the Immunoglobulin kappa locus, IGK@.-Further reading:...
  
  : immunoglobulin kappa constant
• IGKJ@: immunoglobulin kappa joining group
  • IGKJ1, IGKJ2, IGKJ3, IGKJ4, IGKJ5
• IGKV@: immunoglobulin kappa variable group
  • IGKV1-5, IGKV1-6, IGKV1-8, IGKV1-9, IGKV1-12, IGKV1-16, IGKV1-17, IGKV1-27, IGKV1-33
  • IGKV1D-8, IGKV1D-12, IGKV1D-13, IGKV1D-16, IGKV1D-17, IGKV1D-22, IGKV1D-27, IGKV1D-32, IGKV1D-33, IGKV1D-39, IGKV1D-43
  • IGKV2-24, IGKV2-28, IGKV2-30, IGKV2-40
  • IGKV2D-26, IGKV2D-28, IGKV2D-29, IGKV2D-30, IGKV2D-40
  • IGKV3-11, IGKV3-15, IGKV3-20
  • IGKV3D-7, IGKV3D-11, IGKV3D-20
  • IGKV4-1
  • IGKV5-2
• and a number of non-functional and pseudogene
  Pseudogene
  Pseudogenes are dysfunctional relatives of known genes that have lost their protein-coding ability or are otherwise no longer expressed in the cell...
  
  s

Further reading