IFT81
Encyclopedia
Intraflagellar transport protein 81 homolog is a protein
that in humans is encoded by the IFT81 gene
. Together with IFT74/72
it forms a core complex to build IFT particles which are required for cilium
formation. Additionally, it interacts with basal body components as CEP170
which regulates the disassembly of the cilium.
Protein
Proteins are biochemical compounds consisting of one or more polypeptides typically folded into a globular or fibrous form, facilitating a biological function. A polypeptide is a single linear polymer chain of amino acids bonded together by peptide bonds between the carboxyl and amino groups of...
that in humans is encoded by the IFT81 gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
. Together with IFT74/72
IFT74
Intraflagellar transport protein 74 homolog , also known as coiled-coil domain-containing protein 2 and capillary morphogenesis gene 1 protein , is a protein that in humans is encoded by the IFT74 gene....
it forms a core complex to build IFT particles which are required for cilium
Cilium
A cilium is an organelle found in eukaryotic cells. Cilia are slender protuberances that project from the much larger cell body....
formation. Additionally, it interacts with basal body components as CEP170
CEP170
Centrosomal protein 170kDa, also known as CEP170, is a protein that in humans is encoded by the CEP170 gene.- Function :The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells...
which regulates the disassembly of the cilium.