Hypomethylating agent
Encyclopedia
A hypomethylating agent is a drug that inhibits DNA methylation
.
The term "demethylating agent" is also used.
They are undergoing investigation for use in the treatment of tumor
s.
Examples include:
DNA methylation
DNA methylation is a biochemical process that is important for normal development in higher organisms. It involves the addition of a methyl group to the 5 position of the cytosine pyrimidine ring or the number 6 nitrogen of the adenine purine ring...
.
The term "demethylating agent" is also used.
They are undergoing investigation for use in the treatment of tumor
Tumor
A tumor or tumour is commonly used as a synonym for a neoplasm that appears enlarged in size. Tumor is not synonymous with cancer...
s.
Examples include:
- decitabine
- azacitidine