Hypoalphalipoproteinemia
Encyclopedia
Hypoalphalipoproteinemia is a high-density lipoprotein deficiency, inherited in an autosomal dominant manner.
It can be associated with LDL receptor
.
Associated regions and genes include:
Niacin
is sometimes prescribed to raise HDL levels.
LDL receptor
The Low-Density Lipoprotein Receptor is a mosaic protein of ~840 amino acids that mediates the endocytosis of cholesterol-rich LDL. It is a cell-surface receptor that recognizes the apoprotein B100 which is embedded in the phospholipid outer layer of LDL particles...
.
Associated regions and genes include:
| Name | OMIM | Locus | Candidates |
|---|---|---|---|
| HDLCQ1 | 9p | ABCA1 ABCA1 ATP-binding cassette transporter ABCA1 , also known as the cholesterol efflux regulatory protein is a protein which in humans is encoded by the ABCA1 gene... (Tangier disease Tangier disease Tangier disease is a rare inherited disorder characterized by a severe reduction in the amount of high density lipoprotein , often referred to as "good cholesterol," in the bloodstream.-Diagnosis:... ) |
|
| HDLCQ2 | 8q23 | ||
| HDLCQ3 | 16q24.1 | LCAT (Lecithin cholesterol acyltransferase deficiency Lecithin cholesterol acyltransferase deficiency Lecithin cholesterol acyltransferase deficiency is disorder of lipoprotein metabolism.Lecithin cholesterol acyltransferase catalyzes the formation of cholesterol esters in lipoproteins.-Types:The disease has two forms:... ) |
|
| HDLCQ4 | 4q32 | ||
| HDLD3 | 11q23.3 | APOA1 |
Niacin
Niacin
"Niacin" redirects here. For the neo-fusion band, see Niacin .Niacin is an organic compound with the formula and, depending on the definition used, one of the forty to eighty essential human nutrients.Niacin is one of five vitamins associated with a pandemic deficiency disease: niacin deficiency...
is sometimes prescribed to raise HDL levels.