Hodulcine
Encyclopedia
Hodulcine are glycosides (dammarane-type Triterpene), which were isolated from the leaves of Hovenia dulcis
Hovenia dulcis
Hovenia dulcis, the oriental raisin tree, is a hardy tree that occurs from Japan, over Eastern China and Korea to the Himalayas , growing preferably in a sunny position on moist sandy or loamy soils...

 Thunb.
(Rhamnaceae
Rhamnaceae
Rhamnaceae, the Buckthorn family, is a large family of flowering plants, mostly trees, shrubs and some vines.The family contains 50-60 genera and approximately 870-900 species. The Rhamnaceae have a worldwide distribution, but are more common in the subtropical and tropical regions...

) also known as Japanese Raisin Tree.

Several glycosides homologue have been found in this plant and although hoduloside 1 exhibits the highest anti-sweet activity, it is less potent than gymnemic acid 1
Gymnemic acid
Gymnemic acids are glycosides isolated from the leaves of Gymnema sylvestre . Gymnemic acids like ziziphin and hodulcine are anti-sweet compounds, or sweetness inhibitors. After chewing the leaves, solutions sweetened with sucrose taste like water.More than 20 homologues of gymnemic acid are found...

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