Hans Lineweaver
Encyclopedia
Hans Lineweaver was an American
Physical Chemist
, who developed the Lineweaver–Burk plot. The paper containing the equation, also known as the Double Reciprocal Plot, was co-authored by Dr. Dean Burk
, and was entitled "The Determination of Enzyme Dissociation Constants (1934)". It remains the most frequently cited paper ever to appear in the Journal of the American Chemical Society
.
Lineweaver developed the Lineweaver–Burk equation in 1934 while still a graduate student, working as a laboratory assistant under Burk at the US Department of Agriculture in Washington, D.C.
He is an internationally recognized authority on food technology as it is applied to the processing, preservation and safety of poultry and eggs.
in 1930, and continued on to receive his Masters of Arts degree there in 1933. He obtained his PhD in Physical Chemistry from Johns Hopkins University
in 1936. In 1929, a year before graduating, he was appointed a Junior Scientific Aid to the U.S. Department of Agriculture, and worked as a chemist in the fertilizer section of the Bureau of Chemistry and Soils. In 1930, Lineweaver was transferred to the Food Research Division of the USDA as an Associate Chemist pursuing enzyme research. In 1939, he was transferred to the newly-built Western Regional Research Laboratory of the USDA in Albany, California
as Senior Biochemist and head of the enzyme section in the biochemical division. During and after World War II
, Dr. Lineweaver collaborated with the Quartermasters Corps of the Armed Services in enzyme work related to poultry and powdered egg flavor and processing. In 1948, he was appointed Chief of the WRRL Poultry Laboratory in 1949, a position he held until his retirement in 1973, after 44 years of continuous service for the U.S. Department of Agriculture.
During his 44 year career, Dr. Lineweaver was the author or co-author of nearly 100 technical publications and six patents, over half of which deal with some aspects of poultry and eggs, and the remainder with enzymology or other aspects of biochemistry. He and his team developed the first USDA-approved method of pasteurizing egg white, and established a process of converting waste feathers into feed. He has received numerous honors, citations and awards, culminating in the receipt of the Nicholas Appert Award from the Institute of food Technologists (IFT) in 1973. Hans was a President of the IFT in 1971, and was appointed by the State Department to Chair the U.S. Delegation to the 12th World Poultry Congress in Australia in 1962. He was an active member or chairman of numerous organizations, including the American Chemical Society, the Poultry Science Association, the World Poultry Science Association, the Poultry and Egg National Board, the Institute of American Poultry Industries, and the American Society of Biological Chemists.
on Christmas Day, 1907, joining his sister Ruth as the children of Rev. Dr. Jesse Luther and Lucille Lineweaver. He was married in 1936 to Margaret Mary Coon of Baltimore, MD, and is the father of 2, the grandfather of 15, the great-grandfather of 29 and the great-great grandfather of 11. He lived in retirement in Walnut Creek, California
. Lineweaver died in Walnut Creek on June 10, 2009 at age 101.
United States
The United States of America is a federal constitutional republic comprising fifty states and a federal district...
Physical Chemist
Physical chemistry
Physical chemistry is the study of macroscopic, atomic, subatomic, and particulate phenomena in chemical systems in terms of physical laws and concepts...
, who developed the Lineweaver–Burk plot. The paper containing the equation, also known as the Double Reciprocal Plot, was co-authored by Dr. Dean Burk
Dean Burk
Dean Burk was an American biochemist: a co-discoverer of biotin, medical researcher, and a cancer researcher at the Kaiser Wilhelm Institute and the National Cancer Institute...
, and was entitled "The Determination of Enzyme Dissociation Constants (1934)". It remains the most frequently cited paper ever to appear in the Journal of the American Chemical Society
Journal of the American Chemical Society
The Journal of the American Chemical Society is a weekly peer-reviewed scientific journal that was established in 1879 by the American Chemical Society. The journal has absorbed two other publications in its history, the Journal of Analytical and Applied Chemistry and the American Chemical Journal...
.
Lineweaver developed the Lineweaver–Burk equation in 1934 while still a graduate student, working as a laboratory assistant under Burk at the US Department of Agriculture in Washington, D.C.
Washington, D.C.
Washington, D.C., formally the District of Columbia and commonly referred to as Washington, "the District", or simply D.C., is the capital of the United States. On July 16, 1790, the United States Congress approved the creation of a permanent national capital as permitted by the U.S. Constitution....
He is an internationally recognized authority on food technology as it is applied to the processing, preservation and safety of poultry and eggs.
Early life
Lineweaver received his Bachelor of Arts degree in Chemistry from George Washington UniversityGeorge Washington University
The George Washington University is a private, coeducational comprehensive university located in Washington, D.C. in the United States...
in 1930, and continued on to receive his Masters of Arts degree there in 1933. He obtained his PhD in Physical Chemistry from Johns Hopkins University
Johns Hopkins University
The Johns Hopkins University, commonly referred to as Johns Hopkins, JHU, or simply Hopkins, is a private research university based in Baltimore, Maryland, United States...
in 1936. In 1929, a year before graduating, he was appointed a Junior Scientific Aid to the U.S. Department of Agriculture, and worked as a chemist in the fertilizer section of the Bureau of Chemistry and Soils. In 1930, Lineweaver was transferred to the Food Research Division of the USDA as an Associate Chemist pursuing enzyme research. In 1939, he was transferred to the newly-built Western Regional Research Laboratory of the USDA in Albany, California
Albany, California
Albany is a city in Alameda County, California, United States. The population was 18,539 at the 2010 census.-History:In 1908, a group of local women protested the dumping of Berkeley garbage in their community...
as Senior Biochemist and head of the enzyme section in the biochemical division. During and after World War II
World War II
World War II, or the Second World War , was a global conflict lasting from 1939 to 1945, involving most of the world's nations—including all of the great powers—eventually forming two opposing military alliances: the Allies and the Axis...
, Dr. Lineweaver collaborated with the Quartermasters Corps of the Armed Services in enzyme work related to poultry and powdered egg flavor and processing. In 1948, he was appointed Chief of the WRRL Poultry Laboratory in 1949, a position he held until his retirement in 1973, after 44 years of continuous service for the U.S. Department of Agriculture.
During his 44 year career, Dr. Lineweaver was the author or co-author of nearly 100 technical publications and six patents, over half of which deal with some aspects of poultry and eggs, and the remainder with enzymology or other aspects of biochemistry. He and his team developed the first USDA-approved method of pasteurizing egg white, and established a process of converting waste feathers into feed. He has received numerous honors, citations and awards, culminating in the receipt of the Nicholas Appert Award from the Institute of food Technologists (IFT) in 1973. Hans was a President of the IFT in 1971, and was appointed by the State Department to Chair the U.S. Delegation to the 12th World Poultry Congress in Australia in 1962. He was an active member or chairman of numerous organizations, including the American Chemical Society, the Poultry Science Association, the World Poultry Science Association, the Poultry and Egg National Board, the Institute of American Poultry Industries, and the American Society of Biological Chemists.
Personal
Hans Lineweaver was born in Pickens, West VirginiaPickens, West Virginia
Pickens is an unincorporated census-designated place in Randolph County, West Virginia, United States. Pickens is west-southwest of Huttonsville. It is the home of the Cunningham-Roberts Museum. Pickens has a post office with ZIP code 26230. As of the 2010 census, its population was 66....
on Christmas Day, 1907, joining his sister Ruth as the children of Rev. Dr. Jesse Luther and Lucille Lineweaver. He was married in 1936 to Margaret Mary Coon of Baltimore, MD, and is the father of 2, the grandfather of 15, the great-grandfather of 29 and the great-great grandfather of 11. He lived in retirement in Walnut Creek, California
Walnut Creek, California
Walnut Creek is an incorporated city located east of the city of Oakland. It lies in the East Bay region of the San Francisco Bay Area. While not as large as neighboring Concord, Walnut Creek serves as the business and entertainment hub for the neighboring cities within central Contra Costa...
. Lineweaver died in Walnut Creek on June 10, 2009 at age 101.