HMOX1
Encyclopedia
HMOX1 is a human
gene
that encodes for the enzyme heme oxygenase 1
(EC 1.14.99.3). Heme oxygenase is an essential enzyme in heme catabolism, it cleaves heme
to form biliverdin
.
The HMOX gene is located on the long (q) arm of chromosome 22
at position 13.1, from base pair 34,101,636 to base pair 34,114,748.
Human
Humans are the only living species in the Homo genus...
gene
Gene
A gene is a molecular unit of heredity of a living organism. It is a name given to some stretches of DNA and RNA that code for a type of protein or for an RNA chain that has a function in the organism. Living beings depend on genes, as they specify all proteins and functional RNA chains...
that encodes for the enzyme heme oxygenase 1
Heme oxygenase
This reaction can occur in virtually every cell; the classic example is the formation of a bruise, which goes through different colors as it gradually heals: red heme to green biliverdin to yellow bilirubin...
(EC 1.14.99.3). Heme oxygenase is an essential enzyme in heme catabolism, it cleaves heme
Heme
A heme or haem is a prosthetic group that consists of an iron atom contained in the center of a large heterocyclic organic ring called a porphyrin. Not all porphyrins contain iron, but a substantial fraction of porphyrin-containing metalloproteins have heme as their prosthetic group; these are...
to form biliverdin
Biliverdin
Biliverdin is a green tetrapyrrolic bile pigment, and is a product of heme catabolism. It is the pigment responsible for a greenish color sometimes seen in bruises.- Metabolism :...
.
The HMOX gene is located on the long (q) arm of chromosome 22
Chromosome 22 (human)
Chromosome 22 is one of the 23 pairs of chromosomes in human cells. Humans normally have two copies of Chromosome 22 in each cell. Chromosome 22 is the second smallest human chromosome, spanning about 49 million DNA base pairs and representing between 1.5 and 2 % of the total DNA in cells.In 1999,...
at position 13.1, from base pair 34,101,636 to base pair 34,114,748.